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Jeffries Lab publishes paper aimed at identifying potential endpoints for use in the fish embryo acute toxicity test

Jeffries Lab publishes paper aimed at identifying potential endpoints for use in the fish embryo acute toxicity test. Julie Krzykwa (MS Biology 2017, PhD Biology 2020), Alexis Olivas (BS Biology 2017) and Dr. Jeffries published an article in Environmental Toxicology and Chemistry entitled: “Development of Cardiovascular and Neurodevelopmental Metrics as Sublethal Endpoints for the Fish Embryo Toxicity Test.” The article presents research describing methods for measuring cardiovascular and neurological endpoints in fathead minnow embryos and provides evidence indicating that the inclusion of sublethal endpoints may improve the sensitivity of the fish embryo acute toxicity test, which has been proposed a more human alternative to toxicity tests featuring older fish. The article can be viewed at https://setac.onlinelibrary.wiley.com/doi/full/10.1002/etc.4212.

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