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Annual Report

Annual Report

Annual Reports

Awards and Accomplishments

 

Leadership Roles

  • Jeffries, M.
    • Webmaster – South Central Regional Chapter of the Society of Environmental Toxicology and Chemistry
    • Nominating Committee Member – South Central Regional Chapter of the Society of Environmental Toxicology and Chemistry
    • Advisory Committee Member – Health and Environmental Science Institute Animal Alternatives in Environmental Risk Assessment Committee
    • Conference Session Chair – 36th Annual Society of Environmental Toxicology and Chemistry North America Meeting, Aquatic Toxicology and Ecology Session

 

Community Service

  • Gail Jones
  • Board member and Secretary, Wise Hope Domestic Violence Task Force and Shelter, Wise County, Texas

 

 

Student Accomplishments (research accomplishments should be listed in research section below)

 

Best Student Poster Presentation for “Development of the fathead minnow as a model organism for the study of immune function: characterization of molecular responses to pathogen infection” by Thornton LM**, LeSueur MC*, Yost AT*, Stephens DA*, Oris JT, Jeffries MK; Texas Chapter of the American Fisheries Society Annual Meeting, 2015.

 

First place for “Timing is everything: Are the effects of PBDE-47 different in adult and early life stage organisms?” by Thornton, L.; TCU Three Minute Thesis (3MT®) Competition, 2015.

 

People’s choice award for “Timing is everything: Are the effects of PBDE-47 different in adult and early life stage organisms?” by Thornton, L., TCU Three Minute Thesis (3MT®) Competition; 2015.

 

 

 

82 TCU Undergraduate Students Research with Biology Faculty

 

Akkaraju, G.

 

Honor’s Students

Manoj Chelvanambi (BS 2015) Senior Honors Thesis. Estrogen receptor-mediated targeted delivery of DNA-methylating agents to breast cancer cells.

 

Kyle Szymanski (BS 2015) Senior Honors Thesis. Gene delivery to mammalian cells. using silicon microparticles.

 

Allison Simkins (BS 2015) Senior Honors Thesis. Effect of inhibitors of Hepatitis C virus protein NS5A on antiviral gene expression.

 

Elli Hoge (BS 2016) Senior Honors Thesis (In progress) Effect of Hepatitis C virus protein NS5A on the activation of antiviral gene expression.

 

Josey Richards (BS 2016) Senior Honors Thesis (In progress) Effect of Hepatitis C virus protein NS5A on the translocation of transcription factors into the nucleus.

 

Julianna West (BS 2017) Senior Honors Thesis (In progress) NS5A and the degradation of IKB

 

Jordan Talley (BS 2016) Senior Honors Thesis (In progress) Diagnostic test for cancer protein markers in blood.

 

Eric Reid (BS 2017) Senior Honors Thesis (In progress) Hepatitis C Virus Protein NS5A and Inhibition of Interferon β Gene Expression.

 

Michael Chandra (BS 2017) Senior Honors Thesis (In progress) DNA site-specific N3-adenine methylation targeted to estrogen receptor-positive cells.

 

Independent Research Students

 

Athanasios Vousaz (BS 2015) Independent Research Project.

 

Emily Williams (BS 2017) Independent Research (In progress) The Effect of Hepatitis C Virus Non-Structural Protein NS5A on Antiviral Gene Expression.

 

Mary Hamblen (BS 2016) Independent Research (In progress) Diagnostic test for cancer microRNA markers in blood.

 

Chumchal/Drenner – Honor’s Students (*co-advised with Ray Drenner)

Natalie Farha* – Mercury contamination of tetragnathid spiders at the LBJ National

Grassland: Risk to birds

 

Joan Fernandez* – Mercury contamination of tetragnathid spiders at the LBJ National

Grassland: Seasonal variation in Hg concentrations

 

Cameron Keylor* – Relationship between Hg concentrations in aquatic insects and terrestrial spiders

 

Madison Rightley* – Relationship between Hg concentrations in fish and terrestrial spiders

 

Charlie Gober* – Succession of larval aquatic insects in response to drought

 

Ashlyn Courville* – Succession of aquatic insects in response to drought: effects on size

 

Courtney Cochran – Mercury Gulf of Mexico fish.

 

Kyle Lauck* – Mercury in spiders.

 

Kirkland Polk* – Seasonality of small insect emergence from fish and fishless ponds.

 

Macgregor Hall* – Small insect mercury flux from fish and fishless ponds.

 

Maddy Hannappel* – Mercury in mud daubers

 

Independent Research Students (*co-advised with Ray Drenner)

Luke Lossau* – Succession of aquatic insects in response to drought

 

Connor Miller* – Small insect mercury flux from fish and fishless ponds

 

Trey Swinney* – Mercury in spiders

 

Iain Bryant* – Mercury in aquatic insects

 

Chumley, M.

Hailey Hayes, Spring 2015 (Honors Thesis Project: Nuclear Orphan Receptors in Inflammation-Induced Alzheimer’s Pathologies)

 

Laurel Gardner, Spring 2015 (Honors Thesis Project: Tau Hyperphosphorylation Following Inflammation)

 

Troy Gurney, Spring 2015 (Honors Thesis Project: Pyclin Derivatives as a Treatment for Alzheimer’s Disease)

 

Janelle Salisbury, Spring 2015 (Project: Cortocosteroids and Alzheimer’s Disease)

 

Sydney DeSpain, Spring 2015 ­– Fall 2015 (Project: Minimum LPS Dose to Induce Amyloid Beta Production in Aged Mouse Model))

 

Alex Sanders, Spring 2015 ­– Fall 2015 (Project:  Omega-3 Fatty Acids in Inflammation and Alzheimer’s Disease)

 

Jacob Ortega, Spring 2015 (Project: Stress and Inflammation in Alzheimer’s Disease)

 

Laila Abdeljalil, Spring 2015 ­(Project: Western Diet and Inflammation in Alzheimer’s Disease)

 

Jenny Hagemeier, Spring 2015 ­– Fall 2015 (Project:  Bioactive Dendrimer Drugs as Potential Therapeutic Treatments for Inflammation)

 

Kelsey Paulhus, Spring 2015 (Project: Triazine dendrimers as potential disruptors of LPS:TLR4 interactions)

 

Hannah Hefley, Spring 2015 ­– Fall 2015 (Project: TBD)

 

Jake Powel, Summer 2015 – Fall 2015 (Project:  Does Forced Exercise Provide a Benefit to Alzheimer’s Disease Similar to Voluntary Exercise?)

 

Terrul Ratcliff, Summer 2015 – Fall 2015 (Project:  The Interaction Between Exercise and Increased Cerebrospinal Fluid Flow on Amyloid Beta Clearance From the Brain Following Inflammation)

 

Hannah Wilkerson, Summer 2015 – Fall 2015 (Project:  The Role of Exercise in the Anti-Inflammatory Response of Microglial Cells from the Hippocampus)

 

Sruthi Reddy, Summer 2015 – Fall 2015 (Project:  The Expression of NR4A Family Orphan Receptors in Response to Repeated Bouts of Poly:IC Injections)

 

Eleanore Rominger, Summer 2015 – Fall 2015 (Peritoneal B-1 Cells Offer Resistance to LPS-Induced Amyloid Beta Production and May Have Therapeutic Value)

 

Taylor Hayes, Summer 2015 – Fall 2015 (Project:  Resveratrol as a Therapeutic Agent Against Amyloid Beta-Induced Oxidative Stress)

 

Hale, A.

Elizabeth McDowell – Bat abundance and diversity in neighborhoods around TCU (project)

 

Martin McQueen – Behavioral responses to an acoustic deterrent; participation in acoustic surveys, mist netting, and bat care in flight facility (project)

 

Gunnar Nystrom – Bat abundance and diversity around Fort Worth; participation in mist netting and bat care in flight facility (project)

 

Katherine Pfeiffer – Acoustic activity of bats around the TCU campus, participation in mist netting and bat care in flight facility (project)

 

Colby Plott – Bat abundance and diversity around Fort Worth, participation in behavioral experiments in bat flight facility (project)

 

Hale, M.

Courtney Bell (Graduating May 2016)

 

Lauren Burgess (Graduating May 2016)

 

Phil Crain (Graduating May 2018)

 

Christy Smith (Graduating May 2017) Honors project “Determining the placement of genes involved in phototransduction on the rainbow trout genome”.

 

Ben Showalter (Graduating May 2017) Honors project “Using SNP markers to determine the genetic basis of migration in rainbow trout”.

 

Sam Showalter (Graduating May 2017) Honors project “Describing patterns of sex-bias in gene expression in the brain of brook trout”.

 

Jessie Yates (Graduating May 2018)

 

Horner, J.

Haley Rylander, Honors Thesis:  “Soil Hydrology and Nitrogen Filtration in Rain Gardens”

 

Galib Mirza,  Independent Research: “Nectar Production by Capturing and Non-capturing Pitchers of the Carnivorous Plant, Sarracenia alata.”

 

Jeffries, M.

Thomas Boudreaux, 2015-Present, Honors Thesis: “Title TDB”

 

Lauren Burgess, 2015-Present, Project Assistant for “Males, masculinity and immunity: A test of the immunocompetence handicap hypothesis in fathead minnows”

 

Haley Egan, 201-Present, Independent Project: “Sink or swim: Effects of thyroid hormones on the developing fathead minnow immune system.”

 

Meriel LeSueur, 2014-Present, Honors Thesis: “Another fish in the signaling sea: The effect of thyroid hormone on the immune function of adult fathead minnows”

 

Jacob Malmquist, 2014-Present, Honors Thesis: “Effective spawning strategies for producing viable fathead minnow embryos for use in fish embryo toxicity tests.”

 

Alexis Medders, 2014-Present, Honors Thesis: “Males, masculinity and immunity: A test of the immunocompetence handicap hypothesis in fathead minnows”

 

Gunnar Nystrom, 2014-Present, Honors Thesis: “Cause for Concern: Chemical contamination in Kazakhstan’s Syr Darya river and its impacts on fish reproductive health.”

 

Elise Path, 2014-Present, Honors Thesis: “Identifying sensitive indicators of thyroid disruption in fathead minnows after exposure to thyroxine and propylthiouracil”

 

Kate Phillips, 2014-Present, Honors Thesis” “Identifying molecular biomarkers of growth inhibition in fathead minnows: Ontogenetic expression profiles and responses to common contaminants”

 

Kyle Roush, 2014-Present, Honors Thesis: “Enhancing the fish embryo toxicity test: Growth, development abnormalities and gene expression as additional test endpoints”

 

Lydia Stephens, 2014-Present, Independent Project: “Color as a confounder: The effects of background color on metamorphosis and stress responses in the common laboratory model, Xenopus laevis

 

Alexandra Yost, 2014-2015, Honors Thesis: “Global amphibian declines: Are exposures to polybrominated diphenyl ethers a contributing factor?”

 

McGillivray, S

Quynh Ngo: “Overexpression of FtsZ in Bacillus anthracis

 

Madison Rogan: “Investigation of Galleria mellonella as an infection model”

 

Candler Boortz: “Role of ClpX in S. aureus virulence and survival”

 

Misamore, M.

Sarah Gallagher (Senior Honors Thesis) – Sarah was biology major who completed her Senior Honors thesis in my lab.  Here project focuses on the role of temperature during fertilization in quagga mussels.

 

Robert Leonard – Robert is a biology major working on Quagga mussel fertilization and early development.  He is studying the effects of temperature on early development.

 

Williams, D.

Elizabeth Do – Texas yeast diversity (B.S. Biology, 2015, Honors)

 

Sharon Fronk – Diet determination of Texas horned lizards through fecal DNA analyses (B.S. Biology 2015, Project)

 

Kristin Scoggin – Genetic diversity of Fort Worth Texas horned lizards from museum specimens (Honors in progress)

 

Andrew Trinh – Relationship of diet to body size in Texas horned lizards (Phrynosoma cornutum) (Honors in progress).

 

Rachel Alenius – Diet analysis of Texas horned lizards in urban environments (Honors in progress)

 

Mallory Melton – Genetic diversity of Texas horned lizards (Phrynosoma cornutum) in small Texas towns (Project in progress)

 

Kaitlyn Upton – Diet analysis of Texas horned lizards (Project in progress)

 

INNOVATIVE STRATEGIES

  • The Department’s approach to improving the quantity and quality of applicants for the graduate program has continued to evolve. This year we had 29 applicants for five TA positions, the most applicants in the history of the Department.  We only accepted students interested in getting MS degrees, and the quality of the graduate students awarded TA positions was much higher than in previous years, as indicated by higher GRE scores and GPA’s.  Many outstanding applicants were accepted into the program but not given TA positions.

 

 

CHALLENGES IN 2015

  • The greatest challenge in 2015 was to convert Intro Biol I and II from team-taught courses to a course taught by two new instructors. This change in the Intro Biol courses was successful.
  • The department has had to plan for increased enrollments in many courses in 2016 because of increased number of students being admitted to TCU as Biology, Nursing and Kinesiology majors or students who transfer their major after entering TCU. Appendix Figure 1 shows the increases in the number of students enrolled in our core courses.  These core courses have a record number of students enrolled in the courses and we expect this to result in a dramatic increase in students needing our upper level courses.

 

 

 

 

 

GOALS FOR 2016

 

  • Hire tenure-track biochemist
  • Apply for college- and university-level approval of the PhD program in Biology
  • Implement changes in faculty teaching loads necessitated by changes in faculty involvement in Intro Biol I and II.
  • Develop class schedules to accommodate potential increases in enrollment in upper level courses.

 

 

RESEARCH AND SCHOLARLY ACTIVITY

 

Program Highlights/Notable Accomplishments

 

30 Oral Presentations/Posters at Scientific Meetings and Invited Seminars and Awards

 

  • Barst, B.D*, M. Rosabal, P.G.C. Campbell, K. Bridges*, M. Korbas, A.P. Roberts, M. Chumchal, J.D. Smith*, P.E. Drevnick. 2015. Mercury speciation in fish liver at the organ, tissue, and sub-cellular levels: Implications for toxicity. 12th International Conference on Mercury as a Global Pollutant, Jeju, Korea.

 

  • Chumchal, M.M., Adams*, R. Drenner, D. Donato. 2015. Disparity Between Local Government Fish Consumption Advisory Systems For Methyl Mercury And Federal Government Recommendations: A Case Study Of The South Central U.S. 12th International Conference on Mercury as a Global Pollutant, Jeju, Korea. ***Invited presentation.

 

  • Chumchal, M.M. and W. Drenner. 2015. A conceptual model of the transfer of methyl mercury from small man-made ponds to terrestrial food webs via emergent insects. 12th International Conference on Mercury as a Global Pollutant, Jeju, Korea.

 

  • Gann, G.*, C. Powell*, M. Chumchal, Ray W. Drenner. 2015. Mercury-contaminated terrestrial spiders pose a potential risk to songbirds at Caddo Lake (Texas/Louisiana, USA). 12th International Conference on Mercury as a Global Pollutant, Jeju, Korea.

 

  • Speir, S.**, M. Chumchal, R.W. Drenner. W.G. Cocke*, M. Lewis**, H. Whitt**. 2015. Methyl mercury and stable isotopes of nitrogen reveal that a terrestrial spider has a diet of emergent aquatic insects. 12th International Conference on Mercury as a Global Pollutant, Jeju, Korea.

 

  • Soulen, B.*, D. Adams, B. Barst*, J. Smith*, P. Drevnick, M. Chumchal and A.P. Roberts. 2015. Mercury Accumulation and Speciation in the Livers of Marine and Freshwater Fish Species. Indian River Lagoon Symposium, Boca Raton, Florida.

 

  • Becker, J. *, W. Nowlin and M. Chumchal. 2015. Spatial and temporal variability in fish mercury concentrations from a large river system. Society for Environmental Toxicology and Chemistry North America Meeting. Salt Lake City, Utah.

 

  • White, J.D.*, M.J. Eimerbrink*, H.B. Hayes**, A. Hardy*, W. Boehm and M.J. Chumley (October, 2015). Repeated exposure to poly i:c leads to elevations in hippocampal amyloid-beta, cognitive dysfunction, and sustained deficits in burrowing. Society for Neuroscience Annual Conference, Chicago, IL.

 

  • Hodges, S.L.**, M.J. Eimerbrink*, J.D. Wiles**, J.D. White*, L. Peterman*, M.J. Chumley and G.W. Boehm (October, 2015). Effects of MRK-016 on amyloid-beta induced learning deficits in mice in a contextual conditioning paradigm. Society for Neuroscience Annual Conference, Chicago, IL.

 

  • Pendry, R.J.**, R.P. Madigan**, M.D. Eriksson**, D. White*, M.J. Eimerbrink**, M.J. Chumley, and G.W. Boehm, (October, 2015). L. reuteri decreases baseline anxiety, alters fear-related memory, and buffers stress- induced anxiety in C57/BL6 mice. Society for Neuroscience Annual Conference, Chicago, IL.

 

  • Bienz, C.*, V. Bennett, and Hale, 2015, Surface texture discrimination by bats: implications for reducing mortality at wind turbines. 45th Annual Meeting of the North American Society for Bat Research. Monterey, CA.

 

  • Bennett, V.J., and M. Hale, 2015, Exploring potential hypotheses behind bat-wind turbine collisions. American Wind Energy Association (AWEA) Wind Project Siting Seminar. Austin, TX.

 

  • Horner, J. D., Nitrogen resorption from senescing pitchers and the marginal return of prey capture in the carnivorous plant, Sarracenia alata, 27 July 2015, Alberta, Can.

 

  • Sellin Jeffries M.K., A.Y. Yost**, L.M. Thornton**, B.J. Venables, 2015, Brominated flame retardants: Evidence for altered thyroid signaling and neurological development in Xenopus laevis Society of Toxicology and Environmental Chemistry North America 36th Annual Meeting, Salt Lake City, UT.

 

  • Sellin Jeffries M.K., K.S. Roush**, D.A. Stephens**, 2015, Additional endpoints for the fathead minnow FET test: Evaluation of growth, developmental and gene expression metrics. Society of Toxicology and Environmental Chemistry North America 36th Annual Meeting, Salt Lake City, UT.

 

  • Thornton L.M.*, E.M. Path**, G.S. Nystrom**, B.J. Venables, K. Jeffries, 2015, Comparing the effects of PBDEs on reproductive and thyroid function in adult and early life stage fathead minnows. Society of Toxicology and Environmental Chemistry North America 36th Annual Meeting, Salt Lake City, UT.

 

  • Thornton L.M.*, E.M. Path**, G.S. Nystrom**, B.J. Venables, K. Jeffries,2015, The organizational effects of PBDE-47 exposure on reproductive function in early life stage fathead minnows. Society of Toxicology and Environmental Chemistry North America 36th Annual Meeting, Salt Lake City, UT.

 

  • Jeffries MK. 2015. Ecological risk assessment: A framework for assessing pesticide occurrence and ecological effects in the Syr Darya River basin. Workshop on Catalyzing New International Collaborations in Kazakhstan: Pesticide Occurrence and Ecological Effects in the Syr Darya River Basin. Almaty, Kazakhstan.

 

  • Thornton LM**, Yost AT*, LeSueur MC*, Stephens DA*, Jeffries MK. 2015. Development of the fathead minnow as a model organism for immunotoxicity: Characterization of basic immune function parameters. 18th International Symposium on Pollutant Responses in Marine Organisms, Trondheim, Norway.

 

  • Jeffries MK, Yost AY*, Thornton LM**, Venables BJ. 2015. Exposures to PBDE-47 alter development and thyroid-related gene expression in two model organisms, Pimephales promelas and Xenopus laevis. 18th International Symposium on Pollutant Responses in Marine Organisms, Trondheim, Norway.

 

  • Thornton LM**, Path EM,* Nystrom GS,* Venables BJ, Jeffries MK. 2015. Timing is everything: Exploring the differential effects of PBDE exposure in adult and early life stage fathead minnows. 18th International Symposium on Pollutant Responses in Marine Organisms, Trondheim, Norway.

 

  • Sellin Jeffries MK, Stultz AE, Smith AW, Stephens DA*, Roush KS*, Rawlings JM, Belanger SE, Oris JT. 2015. The fish embryo toxicity test as an alternative to the larval growth and survival test: Test sensitivity and alternative endpoints in zebrafish and fathead minnows. Society of Environmental Toxicology and Chemistry Europe 2015 Conference, Barcelona, Spain.

 

  • Yost AT*, Thornton LM**, Path EM*, Venables BJ, Jeffries MK. The effects of a ubiquitous aquatic contaminant, PBDE-47, on growth and thyroid function in fish and amphibians. Texas Chapter of the American Fisheries Society Annual Meeting, Tyler, TX.

 

  • Thornton LM**, LeSueur MC*, Jeffries MK. 2015. Basic aspects of immunity in two teleost model organisms, the fathead minnow and the sheepshead minnow. Texas Chapter of the American Fisheries Society Annual Meeting, Tyler, TX.

 

  • Stephens DA*, Roush KS*, Oris JT, Jeffries MK. 2015. The fathead minnow fish embryo test: An alternative method for evaluating whole effluent toxicity and surface water quality. Texas Chapter of the American Fisheries Society Annual Meeting, Tyler, TX.

 

  • Thornton LM**, LeSueur MC*, Yost AT*, Stephens DA*, Oris JT, Jeffries MK. 2015. Development of the fathead minnow as a model organism for the study of immune function: characterization of molecular responses to pathogen infection. Texas Chapter of the American Fisheries Society Annual Meeting, Tyler, TX.

 

  • Rogan, M.**, M. McGillivray, 2015, Protein tyrosine phosphatase YwlE as a potential regulator of oxidative stress in Bacillus anthracis, Spring Meeting of the Texas Branch of the American Society of Microbiology, New Braunfels, Tx.

 

  • Claunch, K.C.*, C.R. Evans*, and M. McGillivray, 2015, Connection of the ClpXP protease to antibiotic resistance and autolytic activity in Bacillus anthracis, Fall Meeting of the Texas Branch of the American Society of Microbiology, Huntsville TX.

 

  • Gallagher, S., N. Cress, J. Misamore, December, 13, 2015, Fertilization in Quagga Mussels (Dreissena rostriformis bugensis) ‐Effects of temperature and sperm concentration. American Society for Cell Biology, San Diego, CA.

 

  • Granthon, C*, and A. Williams, 2015, Avian malaria and body condition in four species of North American songbirds, American Ornithologists’ Union/Cooper Ornithological Society annual meeting July 28 – August 2, University of Oklahoma, Norman, OK.

 

 

External Grants Pending/Funded or Not funded – 2015

 

Name of PI Funding Agency Grant

Title

Annual Amount Funded Total Grant Year(s) of Grant
FUNDED          
Akkaraju, G. ASVTA Conservation of Nitrogen by a Carnivourous Plant $1,000 $1,000 2015-2016
Hale, M.C. Great Lakes

Fisheries Commission

Behavorial and genetic diversity among ecotypes of Lake Superior brook trout $49,472 $49,472 2015-2016
Jeffries, M.K. AALAS Toward the 3Rs in Fish Toxicity Testing $27,192 $27,192 2015-2016
Jeffries, M.K. AKNU Emerging contaminants and environmental security in the Syr Darya River Basin $7,150 $71,500 2015-2017
Jeffries, M.K. and M. C. Hale The Genome Consortium for Active Teaching Masculinity and immunity: Using global gene expression data to uncover the relationship between sexual ornamentation and pathogen resistance in male fathead minnows $2,300 $2,300 2015
Hale, A. and V. Bennett DOE-EERE Ultrasonic bat deterrent technology $122,138 $123,638 2015-2017
Hale, A. and V. Bennett DOE-EERE Texturizing wind turbine towers to reduce bat mortality $44,705 $249,076 2015-2016
Hale, A. and V. Bennett NextEra Energy Resources Development and testing of a practical deterrent to minimize bat fatalies at wind turbine $78,820 $195,000 2014-2016
Hale, A. and M. Slattery, V. Bennett, and B. Johnson NextEra Energy Resources NextEra Energy Wind Research Initiative: Phase 2 (2013-2015) $479,453 $1,321,032 2013-2015
McGillivray, S. NIH Validation of trans-translation as a target for antibiotic development in S.aureus $31,171 $63,171 2014-2016
Williams, D.A. USACE Improvements of biological control agents of the monoecious biotype of hydrilla in the US $17,082 $17,082 2015-2016
TOTAL FUNDED $862,483 $2,122,463
 
UNFUNDED
Name of PI Funding Agency Grant

Title

Annual Amount Requested Total Grant

Requested

Year(s) of Grant  Requested /

Unfunded

Drenner, R., Chumchal, M., Walker, K.** NSF Spatial Patterns of Mercury Contamination of Game Fish in Ecoregions of the Southeastern United States 0 $197,135 2016-2018

Unfunded

Green, K.,Chumley, M. Alzheimer’s

Association

Assessing the in vivo effects of pyridol derived small molecules 0 $99,792 2015-2017

Unfunded

Green, K., Chumley, M., Boehm, G. NIH Pyridol derived small molecules targeting oxidate stress 0 $376,045 2015-2017

Unfunded

Green, K., Chumely, M., Boehm, G. NIH Determination of BBB permeability and in vivo impact on antioxidant small molecules 0 $155,998 2016-2018

Unfunded

TOTAL UNFUNDED 0 828,970

 

 

 

Internal Grants Funded/Not Funded – 2015

Name of PI Funding Agency Grant

Title

Annual Amount Funded Total Grant Year(s) of Grant
Akkaraju, G. Moncrief Cancer Institute-TCU DAN site-specific N3-adenine methylation targeted to estrogen receptor-positive cells $5,000 $5,000 2015-2016
Chandra, M and Akkaraju, G. SERC Targeting the Estrogen Receptor in Breast Cancer cells with Cytotoxic Drugs $1,374 $1,374 2015-2016
West, J., and Akkaraju, G. SERC NS5A and the degradation of IKB $914 $914 2015-2016
Reid, E., and Akkaraju, G. SERC Hepatitis C Virus Protein NS5A and Inhibition of Interferon β Gene Expression $1,107 $1,107 2015-2016
Williams, E., and Akkaraju, G. SERC The Effect of Hepatitis C Virus Non-Structural Protein NS5A on Antiviral Gen Expression $1,074 $1,074 2015-2016
Courville, A.**

Chumchal, M., Drenner, R.,

SERC Succesion of aquatic insects in response to drought: effects on size $510 $510 2014-2015
Gober, C.**

Chumchal, M., Drenner, R.,

SERC Succession larval aquatic insects in response to drought $338 $338 2014-2015
Farha, N.**

Chumchal, M., Drenner, R.,

SERC Mercury contamination of tetragnathid spiders at the LBJ National Grassland: Seasonal variation in Hg concentrations $715 $715 2014-2015
Fernandez, J.**

Chumchal, M., Drenner, R.,

SERC Mercury contamination of tetragnathid spiders at the LBJ Grassland: Risk to birds

 

$715 $715 2014-2015
Chumchal, M., Drenner, R., Invests in Scholarship Effects of Pond Permanence on Insect-Mediated Mercury Flux from Ponds in the Great Plains $28,409 $28,409 2014-2015
Chumchal, M. RCAF Seasonal transfer of methylmercury out of experimental ponds by emerging dragonflies

 

 

$4,000 $4,000 2015-2016
Lauck K.**

Chumchal, M., Drenner, R.,

SERC Survey of mercury contamination in spiders from the Eagle Mountain Fish Hatchery $879 $879 2015-2016
Cochran, C.**

Chumchal, M.,

SERC Survey of mercury contamination in Gulf of Mexico fish $750 $750 2015-2016
Hayes, T. and M. Chumley SERC Resveratrol as a Therapeutic Agent Against Amyloid Beta-Induced Oxidative Stress $1,351 $1,351 2015-2016
Sanders, A. and M. Chumley SERC Do Omega-3 Fatty Acids Reduce Inflammation Produced by Microglial Cells $1,210 $1,495 2015-2016
Rominger, E. and M. Chumley SERC Peritoneal B-1 Cells Offer Resistance to LPS-Induced Amyloid Beta Production and May Have Therapeutic Value $1,407 $1,500 2015-2016
Reddy, S. and M. Chumley SERC The Expression of NR4A Family Orphan Receptors in Response to Repeated Bouts of Poly:IC Injections $1,305 $1,305 2015-2016
Wilkerson, H. and M. Chumley SERC The Role of Exercise in the Anti-Inflammatory Response of Microglial Cells from the Hippocampus $1,500 $1,500 2015-2016
DeSpain, S. and M. Chumley SERC Minimum LPS Dose to Induce Amyloid Beta Production in Aged Mouse Model $1,305 $1,305 2015-2016
Ratcliff, T. and M. Chumley SERC The Interaction Between Exercise and Increased Cerebrospinal Fluid Flow on Amyloid Beta Clearance From the Brain Following Inflammation $1,500 $1,500 2015-2016
Powell, J. and M. Chumley SERC Does Forced Exercise Provide a Benefit to Alzheimer’s Disease Similar to Voluntary Exercise? $1,447 $1,447 2015-2016
Chumley, M. and Green, K SERC Development of molecular tools for studying the amyloid protein in Alzheimer’s disease $23,387 $23,387 2014-2015
Sanders, A. and Chumley, M. SERC The Use of Omega-3 Fatty Acids to Reduce Peripheral LPS- Induced Inflammation in Alzheimer’s Disease $600 $600 2014-2015
Ortega, J and Chumley, M. SERC Evaluation of the influence of chronic stress on the development of cognitive dysfunction and hallmark Alzheimer’s pathologies $900 $900 2014-2015
Abdeljalil, L and Chumley, M. SERC Effect of high fat and sugar diet on accumulation of brain amyloid beta and associated cognitive deficits.

 

$1,200 $1,200 2014-2015
Abdeljalil, L and Chumley, M. SERC Steroidal Anti-Inflammatories and Their Role in the Progression of Alzheimer’s Disease $1,000 $1,000 2014-2015
Paulhus, K and Chumley, M. SERC Triazine dendrimers as potential disruptors of LPS:TLR4 interactions. $1,000 $1,000 2014-2015
Gardner, G and Chumley, M. SERC The role of imatinib methanesulfonate salt reduction of hippocampal amyloid-beta in the hyperphosphorylation of Tau $1,200 $1,200 2014-2015
Gurney, T and Chumley, M. SERC The Effectiveness of the Antioxidant Pyclen-OH in the Disaggregation of A plaques, Reduction of Oxidative Stress, and Restoration of Cognitive Function in Alzheimer’s Disease $1,000 $1,000 2014-2015
Hayes, H and Chumley, M. SERC How Early Life Inflammation Affects Brain Amyloid-Beta Accumulation and Cognitive Deficits Following Subsequent Inflammation in Aged Mice $1,000 $1,000 2014-2015
Hale, A., and V. Bennett Andrews

Institue

Raising awareness of the diversity and ecology of bats in Texas $2,000 $2,000 2014-2015
Hale, A., and D. Williams Andrews

Institute

Incorporating K-12 outreach into a conservation genetics study and restoration effort for the threatened Texas horned lizard, Phrynosoma cornutum

 

$2,500 $2,500 2014-2015
Hale, M.C. RCAF The genetic basis of freshwater adaption in gulf pipefish (Syngnathus scovelli) $9,996 $9,996 2015-2016
Horner, J. RCAF Conservation of Nitrogen by a Carnivorous Plant $3,901 $3,901 2015-2016
Jeffries, M.K. RCAF Enhancement of the fathead minnow fish embryo toxicity test: Seeking sublethal endpoints as sensitive indicators of chemically-induced adverse effects $3,930 $3,930 2015-2016
Jeffries, M.K. JSFRP Enhancement of the fathead minnow fish embryo toxicity test: Seeking sublethal endpoints as sensitive indicators of chemically-induced adverse effects $6,000 $6,000 2015-2016
Medders, A.**

Jeffries, M.K.

SERC Males, masculinity and immunity: A test of the immunocompetence handicap hypothesis in fathead minnows $1,500 $1,500 2015-2016
Path, E.**

Jeffries, M.K.

SERC Identifying sensitive indicators of thyroid disruption in fathead

minnows after exposure to thyroxine and propylthiouracil

$1,500 $1,500 2015-2016
Roush, K.**

Jeffries, M.K.

SERC Enhancing the fish embryo toxicity test: Growth, development abnormalities and gene expression as additional test endpoints $1,500 $1,500 2015-2016
Roush, K.**

Jeffries, M.K.

JVR Honors Enhancing the fish embryo toxicity test: Growth, development abnormalities and gene expression as additional test endpoints $1,000 $1,000 2015-2016
Phillips, K.**

Jeffries, M.K.

SERC Identifying molecular biomarkers of growth inhibition in fathead minnows: Ontogenetic expression profiles and responses to common contaminants $1,328 $1,328 2015-2016
Malmquist, J.**

Jeffries, M.K.

SERC Effective spawning strategies for producing viable fathead minnow embryos for use in fish embryo toxicity tests $535 $535 2015-2016
Jones, C. TCU QEP A Global Impact on Healthcare with Dr. Ric Bonnell, Dr. John Gibson, Dr. Mary Foley, Dr. David Knight, Dr. John Podgore $5,500 $5,500 2015-2016
Jones, C. TCU QEP Dr. David Knight and Dr. Clark Jones: Healthcare Relief through Teaching $2,220 $2,220 2015-2016
Boortz, C.**

McGillivray, S.

SERC Role of ClpX in S. aureus antimicrobial virulence and survival. $1,499 $1,499 2015-2016
Ngo, O.**

McGillivray, S.

SERC Overexpression of FtsZ in Bacillus anthracis. $1,494 $1,494 2015-2016
Misamore, M. RCAF “Microscopic Analysis of Quagga Mussel Larvae.” $2,853 $2,853 2015-2016
Misamore, M. RCAF “Detection of live zebra/quagga mussel veligers.” $3,915 $3,915 2015-2016
Alenius, R.**

Williams, D.A.

URFC Diet analysis of Texas horned lizards in urban environments $800 $1,000 2015-2016
Scoggin, K.**

Williams, D.A.

SERC Genetic Analysis of Texas Horned Lizards in the Fort Worth/Dallas Area $324 $324 2015-2016
Melton, M.**

Williams, D.A.

SERC Genetic diversity of Texas horned lizards (Phrynosoma cornutum) in small Texas towns $1,492 $1,492 2015-2016
Trinh, A.**

Williams, D.A.

SERC Relationship of diet to body size in Texas horned lizards (Phrynosoma cornutum) $1,089 $1,089 2015-2016
TOTAL FUNDED $140,504 $145,551
   

 

UNFUNDED
Name of PI Funding Agency Grant

Title

Annual Amount Requested Total Grant

Requested

Year(s) of Grant  Requested /

Unfunded

Hagemeier, J and Chumley, M. SERC The effect of β-amyloid on neuron growth and communication 0 $1,200 2014-2015

Unfunded

Medders, A.**

Jeffries, M.K.

JVR Honors Males, masculinity and immunity: A test of the immunocompetence handicap hypothesis in fathead minnows 0 $1,000 2015-2016

Unfunded

Path, E.**

Jeffries, M.K.

JVR Honors Identifying sensitive indicators of thyroid disruption in fathead

minnows after exposure to thyroxine and propylthiouracil

0 $1,000 2015-2016

Unfunded

Misamore, M. TCU Instructional Grant Compound light microscopes with attached video cameras. 0 $35,700 2015-2016

Unfunded

Misamore, M. TCU Instructional Grant Classroom marine aquarium system.

 

 

0 $4,986 2015-2016

Unfuned

Williams, D.A. RCAF Demography of Texas horned lizards living in small towns 0 $4,000 2015-2016

Unfunded

TOTAL UNFUNDED 0 $47,886

 

 

Faculty Scholarship – 12 Publications 2015 

 

Chumchal, M.M. and R.W. Drenner. 2015, An environmental problem hidden in plain sight: small man-made ponds, emergent insects and mercury contamination of biota in the Great Plains,  Environmental Toxicology and Chemistry, v. 34, p. 1197-1205.

 

Gann, G.*, C. Powell*, M.M. Chumchal, R. Drenner. 2015, Mercury-contaminated terrestrial spiders pose a potential risk to songbirds at Caddo Lake, Texas/Louisiana, USA, Environmental Toxicology and Chemistry, v. 34, p. 303-306.

 

Schulwitz, S.E.*, M.M. Chumchal, J.A. Johnson. 2015, Mercury concentrations in birds from two atmospherically contaminated sites in north Texas, USA, Archives of Environmental Contamination and Toxicology, v. 69, p. 390-398.

 

Eimerbrink, M.J.*, J.D. White*, R.J. Pendry**, S.L. Hodges**, L.N. Sadler**, J.D. Wiles**, M.K. Weintraub*,  M.J. Chumley and G.W. Boehm, 2015, Administration of the inverse benzodiazepine agonist MRK-016 rescues acquisition and memory consolidation following peripheral administration of bacterial endotoxin, Behavioral Brain Research, v. 288, p. 50– 53.

 

Groff, P.A., A.M. Hale, and B.A. Whitlock, 2015, Chloroplast lineages in disjunct western North American populations of Swertia perennis (Gentianaceae), Systematic Botany, v. 40, p. 220-228.

 

Korstian, J.M.*, A.M. Hale, and D.A. Williams, 2015, High genetic diversity, large historic population size, and lack of population structure in two North American tree bats, Journal of Mammalogy, v. 96, p. 972-980.

 

Korstian, J.M.*, A.J. Schildt**, V.J. Bennett, D.A. Williams, and A.M. Hale, 2015, A method for PCR-based identification of bat species from fecal samples. Conservation Genetics Resources, v. 7, p. 803-806.

 

McKinney G.J., M.C. Hale, G. Goetz, M. Gribskov, F.P. Thrower, and K.M. Nichols. 2015, Ontogenetic changes in embryonic and brain gene expression in progeny produced from migratory and resident Oncorhynchus mykiss, Molecular Ecology, v. 24, p. 1792-1809.

 

Sellin Jeffries, M.K., A.E. Stultz, A.W. Smith, D.A. Stephens**, J.M. Rawlings, S.E. Belanger, and J.T. Oris, 2015, The fish embryo toxicity test as a replacement for the larval growth and survival test: A comparison of test sensitivity and identification of alternative endpoints in zebrafish and fathead minnows, Environmental Toxicology and Chemistry, v. 34, p 1369-1381.

De la Salud Bea, R. Adam Fine Petraglia, Luque, L.E. 2015, Synthesis, antimicrobial activity and toxicity of analogs of the scorpion venom BmKn peptides, Toxicon, v. 101, p. 79-84.

 

Misamore, M., E. Couch, and S. Barnard, 2015 “Reproductive Biology of Quagga Mussels (Dreissena rostriformis bugensis) with an Emphasis on Lake Mead” in Biology and Management of Invasive Quagga and Zebra Mussels in the Western United States, p. 560.

 

Stewart-Malone, A, M. Misamore, S. Wilmoth, A. Reyes, W.H. Wong, and J.Gross, 2015, The Effect of UV-C Exposure on Larval Survival of the Dreissenid Quagga Mussel, PLOS v.10, p. 7.

 

The Biology Department has had another successful year, with good productivity in the areas of Teaching, Scholarship and Service.

Teaching:

  • Eighteen faculty members in Biology generated 8952 credit hours for over twelve million dollars of tuition ($1414 per cr hr).  Sixty three students received BA and BS degrees in Biology in 2013/2014.  In addition, biology faculty mentored 65 undergraduate and 17 MS graduate students in research.  While rewarding and central to our Department’s mission, the mentorship of students in research is time consuming and a significant part of the teaching effort of the Department.

Scholarship:

  • The record of scholarship in the Department was very good. During 2014, the faculty published 19 peer-reviewed papers, had $759,000 of extramural funding, $131,027 of intramural funding, and presented 53 papers at scientific meetings or invited seminars.

Service:

  • Biology faculty had advising sessions for 810 students.
  • Biologists played an important role on the PreHealth Committee, including conducting 91 mock interviews to prepare students for interviews at medical schools.  Dr. Matt Chumchal and Dr. Shauna McGillivray served as Director and Associate Director of the Pre-Health Professions Institute, respectively.
  • Biology faculty reviewed 42 manuscripts and grants

 

Awards:

  • Dr. Michael Chumley received the Wassenich Award for Student Mentoring, Texas Christian University, September, 2014

New Faculty:

  • The Department hired two instructors, Dr. Laura Lugue De Johnson and Dr. Meredith Mathis, to teach Introductory Biology and Basic Microblology, respectively.

 

Below is a summary of the Department’s scholarship and student mentoring, compiled from faculty annual reports.

19 Published Papers

Bimodal-hybrid heterocyclic amine targeting oxidative pathways and copper mis-regulation in Alzheimer’s disease. (2014) Gonzalez P, da Costa VC, Hyde K, Wu Q, Annunziata O, Rizo J, Akkaraju G, Green KN. Metallomics. 2014 Nov;6(11):2072-82.

Speir, S.L.**, M.M. Chumchal, R.W. Drenner, W.G. Cocke*, M.E. Lewis**, H.J. Whitt**, 2014, Methylmercury and stable isotopes of nitrogen reveal a terrestrial spider consumes emergent aquatic insects. Environmental Toxicology and Chemistry, v. 33: p. 2506-2509.

Weintraub, M.K.*, D. Kranjac*, M.J. Eimerbrink*, S.J. Pearson*, B.T. Vinson*, J. Patel**, W.M. Summers**, T.B. Parnell**, G.W. Boehm, and M.J Chumley. Peripheral administration of polyI:C leads to increased hippocampal amyloid-beta and cognitive deficits in a non-transgenic mouse. Behavioural Brain Research, 2014, 266, 183-187.

Bennett, V.J., and A.M. Hale, 2014, Red aviation lights on wind turbines do not increase bat-turbine collisions, Animal Conservation, v. 17, p. 354-358.

Bennett V.J., A.M. Hale, K.B. Karsten, C.E. Gordon, and B.J. Suson, 2014, Effect of wind turbine proximity on nesting success in shrub-nesting birds, American Midland Naturalist, v. 172, p. 317-328.

Hale A.M., E.S. Hatchett*, J.A. Meyer*, and V.J. Bennett, 2014, No evidence of displacement due to wind turbines in breeding grassland songbirds, The Condor: Ornithological Applications, v. 116, p. 472-482.

Horner, J.D., E.B. Hodcroft**, A.M. Hale, and D.A. Williams, 2014, Clonality, genetic variation, and the origin of isolated western populations of the carnivorous plant, Sarracenia alata, Journal of the Torrey Botanical Society, v. 141, p. 326-337.

Korstian, J.M.*, A.M. Hale, and D.A. Williams, 2014, Development and characterization of microsatellite loci for eastern red and hoary bats (Lasiurus borealis and L. cinereus), Conservation Genetics Resources, v. 6, p. 605-607.

Hale M.C., J. Colletti, S.A. Gahr, J. Scardina, M. Harmon, M. Duge, R.B. Phillips, G.H. Thorgaard, C.E. Rexroad, and K.M. Nichols, 2014, Mapping and expression of candidate genes underlying a major development rate quantitative locus in rainbow trout (Oncorhynchus mykiss).  Journal of Heredity, v. 105, p. 506-520.

Horner, J. D., 2014, Phenology and pollinator-prey conflict in the carnivorous plant, Sarracenia alata, American Midland Naturalist, v. 171, p.153-156.

Sellin Jeffries, M.K., A.J. Kiss, A.W. Smith, and Oris JT, 2014,  A comparison of commercially-available automated and manual extraction kits for the isolation of total RNA from small tissue samples, BMC Biotechnology, v. 14, p. 94.

Sellin Jeffries, M.K., A.E. Stultz, A.W. Smith, J.M. Rawlings, S.E. Belanger, and J.T. Oris, 2014, Alternative methods for toxicity assessments in fish: Comparison of the fish embryo toxicity and the larval growth and survival tests in zebrafish and fathead minnows, Environmental Toxicology and Chemistry, v. 33, p. 2584-2594.

Kolok A.S., M.K. Sellin Jeffries, L. Knight, D.D. Snow, and S.L. Bartelt-Hunt, 2014, The hourglass: A conceptual framework for the transport of biologically active compounds from agricultural landscapes, Journal of the American Water Resources Association , v. 50, p. 266-274.

Kroh, G.C., R.L. Upjohn, and J.E. Pinder III, 2014, Primary conifer succession on a 1915 mudflow in Lassen Volcanic National Park, California, Journal of Ecology and the Natural Environment, v. 6(12), pp. 406-420

 

Ferguson, G.W., W.H. Gehrman, A.M. Brinker, and G.C. Kroh, 2014, Daily and Seasonal Patterns of Natural Ultraviolet Light Exposure of the Western Sagebrush Lizard (Sceloporus graciosus gracilus) and the Dunes Sagebrush Lizard (Sceloporus arenicolus), Herpetologica, 70(1), pp.56-68

Franks, S.E.*, C. Ebrahimi, A. Hollands, C.Y. Okumura, R.V. Aroian, V. Nizet, and S.M. McGillivray, 2014, A novel role for tellurium resistance genes in the pathogenesis of Bacillus anthracis, Infection and Immunity, v. 82, p. 1132-40.

Wheeler, G., D.A. Williams, and M. Chawner, 2014, Predicting the host range of Nystalea ebalea: secondary plant chemistry and host selection by a surrogate biological control agent of Schinus terebinthifolia, Biological Control, v. 73, p. 39-49.

Diaz, R., D. Moscosoa, V. Manrique, D.A. Williams, and W.A. Overholt, 2014, Native range density, host utilization and life history of Calophya latiforceps (Hemiptera: Calophyidae): An herbivore of Brazilian peppertree (Schinus terebinthifolia), Biocontrol Science and Technology, v. 24, p. 536–553.

Manrique, V., R. Diaz, L. Erazo, N. Reddi, G.S. Wheeler, D.A. Williams, and W.A. Overholt, 2014, Comparison of two populations of Pseudophilothrips ichini (Thysanoptera: Phlaeothripidae) as candidates for biological control of the invasive weed Schinus terebinthifolia (Sapindales: Anacardiaceae), Biocontrol Science and Technology, v. 24, p. 518–535.

$759,849 of External Grants

Chumchal, M and R. Drenner.  NextEra Energy Wind Research Initiative Analysis of Hg contamination in fish from the Southeastern U.S. $10,000 2014

Chumley, M J. Norman Hackerman Advanced Research Program. Chumchal, M and R. Drenner.  NextEra Energy Wind Research Initiative Analysis of Hg contamination in fish from the Southeastern U.S. $10,000 2014

Project Title:  Systemic Inflammation as a Treatable Risk Factor in the Onset of Alzheimer’s Pathology. Contract No.: THECB#9424. 7/01/2012 – 8/31/2014.  $80,000.

Hale AM. (Co-PI with V. Bennett) Development and testing of a practical deterrent to minimize bat fatalities at wind turbines.  2014-2016 NextEra Energy Resources $78,820

Hale AM. NextEra Energy Wind Research Initiative: Phase 2 (2013-2015) (Co-PI with M. Slattery, V. Bennett, and B. Johnson) NextEra Energy Resources $479,453

 

Snow, D.D., A.S. Kolok, S.L. Bartelt-Hunt and M.K. Jeffries        National Science Foundation (NSF)  US-Kazakhstan workshop and pilot study – Pesticide occurrence and ecological effects in the Syr Darya River Basin.  $49,751   2014-2015

 

Thornton L.M.**(student grant submitted under Dr. Jeffries’ supervision)  Sigma Xi           Illuminating the influences of sex-steroid hormones on immune function in the sheepshead minnow.           $825     2014

 

McGillivray, S. NIH       Validation of trans-translation as a target for antibiotic development in S. aureus.            $32,000            $64,000 2014-2016

 

Williams, D.A.  USDA   Quarantine Risk Assessment Studies for Classical Biological Control of Brazilian pepper.  $20,000              2014-2015

 

Williams, D.A.  USACE Improvement of biological control agents for the monoecious biotype of hydrilla in the United States.  $9,000              2014-2015

 

$131,027 of Intramural Grants

Akkaraju G.  TCU RCAF (Research) (June 1, 2014) $3750

Akkaraju G. TCU Global Innovator Proposal (Research) (June 2014) $25000

Rightley, M., R. Drenner and M. Chumchal.  TCU SERC Relationship between Hg concentrations in fish and terrestrial spiders.$1,500 2013-2014

  1. Chumchal. TCU Research and Creative Activities Habitat-specific variation in insect-mediated mercury flux from Caddo Lake $2,800 2013-2014
  1. Courvillle, R. Drenner and M. Chumchal. TCU SERC Succession of aquatic insects in response to drought: effects on size. $510 2014-2015
  1. Gober, R. Drenner and M. Chumchal. TCU SERC Succession of larval aquatic insects in response to drought. $338 2014-2015
  1. Farha, R. Drenner and M. Chumchal. TCU SERC Mercury contamination of tetragnathid spiders at the LBJ National Grassland: Seasonal variation in Hg concentrations. $715 2014-2015
  1. Fernandez, R. Drenner and M. Chumchal. TCU SERC Mercury contamination of tetragnathid spiders at the LBJ National Grassland: Risk to birds. $715 2014-2015
  1. Chumchal and R. Drenner. TCU Invests in Scholarship Effects of Pond Permanence on Insect-Mediated Mercury Flux from Ponds in the Great Plains. $28,409 2014-2015

 

Chumley, M. and Green, K            TCU IS  Development of molecular tools for studying the amyloid protein in Alzheimer’s disease   $23,387  2014-2015

Sanders, A. and Chumley, M.       TCU SERC   The Use of Omega-3 Fatty Acids to Reduce Peripheral LPS- Induced Inflammation in Alzheimer’s Disease.  $600         2014-2015

Ortega, J and Chumley, M.            TCU SERC   Evaluation of the influence of chronic stress on the development of cognitive dysfunction and hallmark Alzheimer’s pathologies.  $900 2014-2015

Abdeljalil, L and Chumley, M.       TCU SERC   Effect of high fat and sugar diet on accumulation of brain amyloid beta and associated cognitive deficits. $1,200         2014-2015

Salisbury, J and Chumley, M        TCU SERC   Steroidal Anti-Inflammatories and Their Role in the Progression of Alzheimer’s Disease.  $1,000     2014-2015

Paulhus, K and Chumley, M.        TCU SERC   Triazine dendrimers as potential disruptors of LPS:TLR4 interactions.  $1,000      2014-2015

Gardner, G and Chumley, M.        TCU SERC   The role of imatinib methanesulfonate salt reduction of hippocampal amyloid-beta in the hyperphosphorylation of Tau.  $1,200       2014-2015

Gurney, T and Chumley, M.          TCU SERC   The Effectiveness of the Antioxidant Pyclen-OH in the Disaggregation of AB plaques, Reduction of Oxidative Stress, and Restoration of Cognitive Function in Alzheimer’s Disease.  $1,000     2014-2015

Hayes, H and Chumley,  M.          TCU SERC   How Early Life Inflammation Affects Brain Amyloid-Beta Accumulation and Cognitive Deficits Following Subsequent Inflammation in Aged Mice.  $1,000            2014-2015

 

  1. Hale (Co-PI with V. Bennett) Andrews Institute Raising awareness of the diversity and ecology of bats in Texas.    $2,000            2014-2015

 

  1. Hale (Co-PI with D. Williams) Andrews Institute Incorporating K-12 outreach into a conservation genetics study and restoration effort for the threatened Texas horned lizard, Phrynosoma cornutum.  $2,500    2014-2015

 

Horner JD.  Research.  TCU RCAF.  Conservation of Nitrogen by a Carnivorous Plant.  $3901.  Funded.

 

Jeffries, M.K.  TCU RCAF Development and validation of a small fish model for assessing the effects of emerging contaminants on immune function.  $3988        2014

Jeffries, M.K. TCU JSFRP Development and validation of a small fish model for assessing the effects of emerging contaminants on immune function.  $6000        2014

Yost, A.** (student grant submitted under Dr. Jeffries’ supervision) TCU SERC Global amphibian declines: Are exposures to polybrominated diphenyl-ethers a contributing factor?  $1500            2014

Stephens, D.** (student grant submitted under Dr. Jeffries’ supervision)TCU SERC       Seeking animal alternatives in toxicity testing: Validation and enhancement of the fathead minnow fish embryo toxicity test as an alternative to larval fish toxicity tests.  $1500        2014

 

McGillivray SM.  2014-2015 SERC (Madison Rogan): Galleria mellonella as an infection model to study the pathogenesis of Bacillus anthracis. Funded $1499.

 

Misamore, M.  2014-2015 TCU RCAF. “Detection of live zebra/quagga mussel veligers.” ($3,915 funded).

 

Williams, D.A. RCAF  Demography of Texas horned lizards living in small towns.  $4,000 2014-2015

 

Williams, D.A.  Andrews Institute   Incorporating K-12 outreach into conservation efforts for the threatened Texas horned lizard.  $2,500 2014-2015

Do, E. and Williams, D.A.   SERC Analysis of yeast DNA sequences to determine unique yeast species to Texas that are optimal for distilling whiskey.  $1,500 2014-2015

Scoggin, K and Williams, D.A.  SERC    Genetic Analysis of Texas Horned Lizards in the Fort Worth/Dallas Area.  $1,200  2014-2015

53 Oral Presentations/Posters at Scientific Meetings and Invited Seminars and Awards

In Vitro analysis of surface modified stain etched porous silicon. Wareing, N, Akkaraju, G., Tian, Y., Rodriguez,, R., Loni, A., Canham, L.T., Coffer, J. Poster presented at PSST2014, March 9-14, 2014, Alicante, Valencia, Spain.

Treatment of Alzheimer’s disease with bimodal hybrid heterocyclic amine ligands: A closer look into the oxidative pathways and copper misregulation in the disease. P. Gonzalez, G. Akkaraju, K. Green. Poster presented at the 247th ACS National Meeting and Exposition, March 16-20, 2014, Dallas, Texas.

Hybrid small molecules using lipoic acid as antioxidant chelators designed to target amyloid and the molecular feastures associated with neurodegenerative disorders. K. N. Green, P. M. Gonzalez, K. M. Lincoln, G. Akkaraju. Poster presented at the 247th ACS National Meeting and Exposition, March 16-20, 2014, Dallas, Texas.

Silicon Nanotube-based drug delivery/gene therapy. Y. Tian, R. Gonzalez-Rodriguez, J. L. Coffer, G. R. Akkaraju. Poster presented at the 247th ACS National Meeting and Exposition, March 16-20, 2014, Dallas, Texas.

DNA binding, DNA methylation and cell toxicity of estradiol conjugated DNA methylating compounds. M. Powell, S. Miller, R. Kishton, K. Mastro, M. Chelvanambi, A. Linares, V. K. Gore, G. R. Akkaraju, S. Varadarajan. Poster presented at the 247th ACS National Meeting and Exposition, March 16-20, 2014, Dallas, Texas.

Inhibition of virus-induced Interferon beta gene expression by mutants of NS5A and their effect on HCV replication. Wu, W., Gleaton, J., Richards, J., Toal, C.,

Chelvanambi, M., and Akkaraju, G. Poster presented at IUMS2014, Montreal QC, July 28-August 1, 2014.  Testing a drug against breast cancer targeting the estrogen receptor. M.

Chelvanambi, R. Kishton, S. Varadarajan, G. Akkaraju. Poster presented at the American Society for Microbiology- Texas Chapter meeting in Houston, TX, Fall 2014.

Adams, K.*, R.W. Drenner and M.M. Chumchal, 2014, Do fish consumption advisories for mercury adequately protect the public?, Texas Academy of Science Annual Meeting, Galveston, Texas.

Adams, K.*, R.W. Drenner and M.M. Chumchal, 2014, Do fish consumption advisories for mercury adequately protect the public? Joint Aquatic Sciences Meeting. Portland, Oregon.

 

Chumchal, M.M. and R.W. Drenner, 2014, Small farm ponds in the Great Plains and the contamination of terrestrial food chains with mercury, Texas Academy of Science Annual Meeting, Galveston, Texas.

 

Chumchal, M.M. and R.W. Drenner, 2014, Small farm ponds in the Great Plains and the contamination of terrestrial food chains with mercury, Joint Aquatic Sciences Meeting, Portland, Oregon.

 

Drenner, R.W., M.M. Chumchal, K. Adams*, 2014, Effects of mercury deposition, coniferous forests, and fish size on mercury contamination of game fish in the south central U.S., Texas Academy of Science Annual Meeting, Galveston, Texas.

 

Drenner, R.W., M.M. Chumchal, K. Adams*, 2014, Effects of mercury deposition, coniferous forests, and fish size on mercury contamination of game fish in the south central U.S., Joint Aquatic Sciences Meeting. Portland, Oregon

Gann, G.*, C. Powell*, M.M. Chumchal, R. Drenner, 2014, Mercury-contaminated terrestrial spiders pose a potential health risk to songbirds at Caddo Lake, TX/LA, Texas Academy of Science Annual Meeting, Galveston, Texas.

Gann, G.*, C. Powell*, M.M. Chumchal, R. Drenner, 2014, Mercury-contaminated terrestrial spiders pose a potential health risk to songbirds at Caddo Lake, TX/LA, Joint Aquatic Sciences Meeting, Portland, Oregon.

Powell, C.*, G. Gann*, M.M.Chumchal, R.W. Drenner, 2014, Hg contaminated riparian spiders along three east Texas rivers pose a potential risk to song birds, Texas Academy of Science Annual Meeting, Galveston, Texas.

Soulen, B.*, D. Adams, B. Barst*, J. Smith*, P. Drevnick, M.M. Chumchal and A.P. Roberts, 2014, Mercury accumulation and speciation in the livers of marine and freshwater fish species, Society for Environmental Toxicology and Chemistry North America Meeting, Victoria, British Colombia, Canada.

Speir, S.**, M.M. Chumchal, R.W. Drenner, G. Cocke*, M. Lewis**, H. Whitt**, 2014, Use of methyl mercury as a tracer of aquatic carbon flux to terrestrial consumers, Texas Academy of Science Annual Meeting, Galveston, Texas.

Speir, S.**, M.M. Chumchal, R.W. Drenner, G. Cocke*, M. Lewis**, H. Whitt**, 2014, Use of methyl mercury as a tracer of aquatic carbon flux to terrestrial consumers, Joint Aquatic Sciences Meeting, Portland, Oregon.

White, J.D.*, M.K. Weintraub*, M.J. Eimerbrink*, A.L. Morin*, S.M. Turner**, S.L. Hodges**, L.N. Sadler**, G.W. Boehm and M.J. Chumley, 2014, Voluntary Exercise Reduces Alzheimer’s-like Pathology After Inflammation in Mice. Society for Neuroscience, Washington, D.C.

Weintraub, M.K.*, J.D. White*, S.M. Turner**, S.L. Hodges**, A.L. Morin*, L.N. Sadler**, G.W. Boehm and M.J. Chumley, 2014, Voluntary Exercise Reduces Alzheimer’s-like Pathology After Inflammation in Mice, Texas Chapter of the American College of Sports Medicine, Fort Worth, TX.

Bennett, V.J., A.M. Hale, A.J. Schildt**, B.G. Cooper, A.M. McAlexander*, and D.A. Williams, 2014, Exploring potential hypotheses behind bat-wind turbine collisions. National Wind Coordinating Collaborative Wind Wildlife Research Meeting X. Broomfield, CO.

Hale, A.M., and VJ Bennett, 2014, Investigating the benefits of fine-tuning curtailment strategies at operational wind facilities. National Wind Coordinating Collaborative Wind Wildlife Research Meeting X. Broomfield, CO.

Bennett, V.J., A.M. Hale, A.J. Schildt**, and DA Williams, 2014, Evidence that bats utilize wind turbines as a foraging resource. National Wind Coordinating Collaborative Wind Wildlife Research Meeting X. Broomfield, CO.

Bennett, V.J., A.M. Hale, A.J. Schildt**, B.G. Cooper, A.M. McAlexander*, and D.A. Williams, 2014, Exploring potential hypotheses behind bat-wind turbine collisions. 44th Annual Meeting of the North American Society for Bat Research. Albany, NY.

Hale, A.M., and V.J. Bennett, 2014, Investigating the benefits of fine-tuning curtailment strategies at operational wind facilities. 44th Annual Meeting of the North American Society for Bat Research. Albany, NY.

Korstian, J.M.*, A.J. Schildt**, V.J. Bennett, D.A. Williams, and A.M. Hale, 2014, A method for PCR-based identification of species from bat fecal samples. 44th Annual Meeting of the North American Society for Bat Research. Albany, NY.

Hale, A.M., E.S. Hatchett*, T.K. Stevens*, J.A. Meyer*, T.G. Rubenstahl*, K.B. Karsten, and V.J. Bennett, 2014, Limited evidence of indirect effects of wind turbines on grassland songbirds. Joint Meeting of the American Ornithologists’ Union, the Cooper Ornithological Society, and the Society of Canadian Ornithologists. Estes Park, CO.  Invited Symposium

Bennett, V.J., A.M. Hale, A.J. Schildt**, and D.A. Williams, 2014, Evidence that bats utilize wind turbines as a foraging resource. American Society of Mammalogists Annual Meeting. Oklahoma City, OK.

Slattery, M., A.M. Hale, and V.J. Bennett, 2014, Environmental, social, and economic impacts of utility-scale wind energy projects. 7th World Future Energy Summit. Abu Dhabi, United Arab Emirates.

Hale, A.M., 2014, Bat mortality at wind turbines: why is it happening and can we lessen the impacts? Invited Seminar, Department of Biological Sciences, Sam Houston State University, Huntsville, TX.

Hale, A.M., and V.J. Bennett, 2014. Impacts of wind energy on bats: research priorities and innovations to reduce bat mortality. General Electric, Greenville, SC.

Hale, A.M., 2014. Impacts of wind energy on birds and bats. Ministry of Natural Resources, Peterborough, Ontario, Canada.

Hale, A.M., 2014, Wind energy and bats – can we lessen the impacts? Invited Seminar, Department of Biology, Baylor University, Waco, TX.

Hale, A.M., V.J. Bennett, B.L. Johnson, and K. Wyrick*, 2014, TCU’s women of wind: a panel discussion on wind energy, wind-wildlife issues, and social politics associated with wind energy. American Association of University Women (AAUW) Tarrant County (TX) Branch January Meeting. Sponsored by the TCU Women’s Studies Program.

Hale, A.M., and V.J. Bennett, 2014. Impacts of wind energy on bats: research priorities and innovations to reduce bat mortality. NextEra Energy Resources, Juno Beach, FL.

Schatz, B. A.** and J. D. Horner, Making the most of a meal: Nitrogen resorption from senescing pitchers and the benefit of prey capture in the carnivorous plant, Sarracenia alata, 13 August 2014, Sacramento, CA, Ecological Society of America national meeting.

 

Sellin Jeffries, M.K., C. Claytor, W. Stubblefield, W. Pearson, and J.T. Oris, 2014, The development and application of a quantitative model to estimate the risk of PAH phototoxicity in Pacific Herring (Clupea pallasi) following the Exxon Valdez oil spill. Society of Environmental Toxicology and Chemistry Asia/Pacific 2014 Conference, Adelaide, Australia.

 

Sellin Jeffries, M.K., A.E. Stultz, A.W. Smith, D. Stephens**, J. Rawlings, S. Belanger, and J.T. Oris, 2014, Animal alternatives in whole effluent toxicity testing: Evaluation of the fathead minnow embryo test as a replacement for the larval growth and survival test. South Central Chapter of the Society of Environmental Toxicology and Chemistry Annual Meeting, San Marcos, TX.

Yost, A.**, A. Lisner**, K. Cox**, Jeffries M, 2014, The effects of fluoride on thyroid hormone signaling and metamorphosis in Xenopus laevis. South Central Chapter of the Society of Environmental Toxicology and Chemistry Annual Meeting, San Marcos, TX.

Thornton, L.*, A. Yost**, M. LeSueur**, D. Stephens**, Jeffries M, 2014, Development of the fathead minnow as a model organism for immunotoxicity: Characterization of basic immune function parameters. South Central Chapter of the Society of Environmental Toxicology and Chemistry Annual Meeting, San Marcos, TX.

Claunch, K.C.**, C.R. Evans*, S.M. McGillivray, 2014, Connection of the ClpXP protease to autolytic activity and antibiotic resistance in Bacillus anthracis,114th General Meeting of the American Society of Microbiology, Boston, MA.

Huang, Y.*, J. Alumasa, K.C. Keiler, S.M. McGillivray, 2014, Small molecule inhibition of trans-translation impairs Staphylococcus aureus viability, Annual Meeting of the Texas Branch of the American Society of Microbiology, Houston TX.

S.M. McGillivray Invited Conference Speaker in 2014 Texas Branch of the American Society of Microbiology Annual Meeting, Houston TX, Nov 2014

Sawey, M., 2014, University Student Responses to the Inclusion of Environmental Curricula, North American Association of Environmental Educators (NAAEE), Ottawa, Canada.

Bennett, V.J., A.M. Hale, A.J. Schildt, B.G. Cooper, A.M. McAlexander, and D.A. Williams, 2014, Exploring potential hypotheses behind bat-wind turbine collisions, National Wind Coordinating Collaborative Wind Wildlife Research Meeting X, Broomfield, CO.

Bennett, V.J., A.M. Hale, A.J. Schildt, and D.A. Williams, 2014, Evidence that bats utilize wind turbines as a foraging resource, National Wind Coordinating Collaborative Wind Wildlife Research Meeting X, Broomfield, CO.

Bennett, V.J., A.M. Hale, A.J. Schildt, B.G. Cooper, A.M. McAlexander, and D.A. Williams, 2014, Exploring potential hypotheses behind bat-wind turbine collisions, 44th Annual Meeting of the North American Society for Bat Research, Albany, NY.

Biffi, D., and D.A. Williams, 2014, Uso de técnicas no-invasivas para determinar tamaño poblacional de Lontra felina en dos localidades de Peru, IV Congreso Nacional de Ciencias del Mar, Lima, Peru.

Biffi, D., and D.A. Williams, 2014, Non-invasive estimation of population size and density of marine otters Lontra felina in Perú, XXII IUCN OSG International Otter Congress, Rio de Janeiro, Brazil.

Korstian, J.M., A.J. Schildt, V.J. Bennett, D.A. Williams, and A.M. Hale, 2014, A method for PCR-based identification of species from bat fecal samples, 44th Annual Meeting of the North American Society for Bat Research, Albany, NY.

 

Williams, D.A., and D. Biffi, 2014, Weak genetic structure of marine otters (Lontra felina) along the coast of Perú, XXII IUCN OSG International Otter Congress, Rio de Janeiro, Brazil.

Wall, A.E., D. Biffi, and D.A. Williams, 2014, Movement and genetics of Texas horned lizards, 117th Annual Meeting of the Texas Academy of Science, Galveston, TX.

66 TCU Undergraduate Students Conducted Research with Biology Faculty

Akkaraju

Coralee Toal

Nancy Wareing

Manoj Chelvanambi

Athanasios Vouzas

Kyle Szymanski

Allison Simkins

Elli Hoge

Josey Richards

 

Chumchal/Drenner

Shannon Speir

Natalie Farha

Joan Fernandez

Cameron Keylor

Madison Rightley

Charlie Gober

Courtney Cochran

Ashlyn Courville

Trey Swinney

Ian Bryant

Conner Glass

Luke Lossau

Chumley

Christine Riddle

Jessica Mussatto

Stephanie Turner

Thomas Parnell

Ceci Canelos

Brock Boren

Tanner Robertson

Hailey Hayes

Laurel Gardner

Troy Gurney

Janelle Salisbury

Sydney DeSpain

Alex Sanders

Jacob Ortega

Laila Abdeljalil

Jenny Hagemeier

Kelsey Paulhus

Hannah Hefley

Hale

Gunnar Nystrom

Elizabeth McDowell

Horner

Ben Schatz

Brandon Zsigray

Jefferies

Alexandra Yost

Kyle Roush

Elise Path

Alexis Medders

Meriel LeSueur

Dane Stephens

Hana Jaafari

Gunnar Systrom

Lydia Stephens

McGillivray

Kevin Claunch

Mariah Green

Madison Rogan

Candler Boortz

Quynh Ngo

Misamore

Rebecca Roozbeh

Ben Clifford

Elizabeth St. Laurent

Ellie Seno

Omar Kahn

Williams

Tanner Campbell

Lizzy Do

Sharon Fronk

Kristin Scoggin

Andrew Trinh

17 TCU Graduate Students Worked on MS Degrees with Biology Faculty

 

Chumchal/Drenner

Kimberly Adams

Gretchen Gann

Cleve Powell

Frank Greenhill

 

Chumley

Marielle Weintraub

Scott Pearson

Amy Hardy

Jordon White

 

Hale

Cecily Foo

Christina Bienz

Luyi Z. Jarzombek

Brad Yuen

 

Jefferies

Leah Thornton

McGillivray

Yueyang Huang

Kevin Claunch

Williams

Ashley Wall

Carolina Granthon

The Biology Department had a very productive year for 2013.    The following is our 2013 annual report.

Teaching:

  • Eighteen faculty members in Biology generated 9032 credit hours for over nine million dollars of tuition.  Sixty five students received BA and BS degrees in Biology in 2012/2013.  In addition, biology faculty mentored 57 undergraduate and 19 MS graduate students in research.  While rewarding and central to our Department’s mission, the mentorship of students in research is time consuming and a significant part of the teaching effort of the Department.

Scholarship:

  • The record of scholarship in the Department was very good. During 2013, the faculty published 13 peer-reviewed papers, had $662,819 of extramural funding, $96,838 of intramural funding, and presented 33 papers at scientific meetings or invited seminars.

Service:

  • Biology faculty had advising sessions for 785 students.
  • Biologists played an important role on the PreHealth Committee, including conducting 66 mock interviews to prepare students for interviews at medical schools.  Dr. Matt Chumchal and Dr. Shauna McGillivray served as Director and Associate Direct of the Pre-Health Professions Institute, respectively.
  • Biology faculty reviewed 25 manuscripts and grants

 

Awards:

  • Dr. Michael Chumley was chosen as a John V. Roach Honors College Professor of the Year Award, April 2013

Below is a summary of the Department’s scholarship and student mentoring, compiled from faculty annual reports.

 13 Published Papers

Fe3O4-nanoparticles within porous silicon: Magnetic and cytotoxicity characterization, 2013, P. Granitzer, K. Rumpf, Y. Tian, G. Akkaraju, J. Coffer, P. Poelt, and M. Reissner, Applied Physics Letters, v.102, 1931110.

Lavoie, R.*, T. Jardine, M.M. Chumchal, K. Kidd, L. Campbell, 2013, Biomagnification of mercury in aquatic food webs: a worldwide meta-analysis, Environmental Science and Technology, v. 47, p. 13385–13394.

Barst, B., C. Hammerschmidt, M.M. Chumchal, D. Muir, J. Smith, A.P. Roberts, T. Rainwater, P. Drevnick, 2013, Determination of mercury speciation in fish tissue with a Direct Mercury Analyzer, Environmental Toxicology and Chemistry, v. 32, p. 1237-1241.

Drenner, R.W., M.M. Chumchal, C.M. Jones*, Christopher M. B. Lehmann, David A.Gay, David I. Donato, 2013, Effects of mercury deposition and coniferous forests on the mercury contamination of fish in the south central United States, Environmental Science and Technology, v. 47, p. 1274-1279.

Jones, T.A.*, M.M. Chumchal, R.W. Drenner, G.N. Timmins, W.H. Nowlin, 2013, Bottom-up nutrient and top-down fish impacts on mercury flux from aquatic ecosystems,  Environmental Toxicology and Chemistry, v. 32, p. 612–618.

Tweedy, B.N.*, R.W. Drenner, M.M. Chumchal, J.H. Kennedy, 2013, Effects of fish on emergent insect-mediated flux of methyl mercury across a gradient of contamination, Environmental Science and Technology, v. 47, p. 1614-1619.

Zapp Sluis, M.*, K.M. Boswell, M.M. Chumchal, R.J.D. Wells, B. Soulen**, J.H. Cowan, Jr., 2013, Regional variation in mercury and stable isotopes of red snapper (Lutjanus campechanus) in the northern Gulf of Mexico, USA,  Environmental Toxicology and Chemistry, v. 32, p. 434-441.

Weintraub, M. K.*, C. M. Bisson**, J. N. Nouri**, B. T. Vinson*, M. J. Eimerbrink*, D. Kranjac*, G. W. Boehm and M. J. Chumley, 2013, Imatinib methanesulfonate reduces hippocampal amyloid-beta and restores cognitive function following repeated endotoxin exposure. Brain Behav Immun, 33, 24-28.

Kranjac, D.*, K. M. Koster**, M. S. Kahn*, M. J. Eimerbrink*, B. M. Womble**, B. G. Cooper, M. J. Chumley and G. W. Boehm, 2013, Peripheral administration of D-cycloserine rescues memory consolidation following bacterial endotoxin exposure. Behav Brain Res, 243, 38-43.

Hatchett, E.S.*, A.M. Hale, V.J. Bennett, and K.B. Karsten, 2013, Wind turbines do not negatively affect nest success in the Dickcissel (Spiza americana), The Auk, v. 130, p. 520-528.

Korstian, J.M.*, A.M. Hale, V.J. Bennett, and D.A. Williams, 2013, Advances in sex determination in bats and its utility in wind-wildlife studies, Molecular Ecology Resources, v. 13, p. 776-780.

Stevens, T.K.*, A.M. Hale, K.B. Karsten, and V.J. Bennett, 2013, An analysis of displacement from wind turbines in a wintering bird community, Biodiversity and Conservation, v. 22, p. 1755-1767.

 

Wheeler, G.S., F. Mc Kay, M. Vitorino, and D.A. Williams, 2013, Biology and host range of Omolabus piceus (Coleoptera: Attelabidae), a weevil rejected for biological control for Schinus terebinthifolius in the USA. Biocontrol, v. 58, p.693-702.

 

$662,819 of External Grants

Chumley, M J. Norman Hackerman Advanced Research Program.

Project Title:  Systemic Inflammation as a Treatable Risk Factor in the Onset of Alzheimer’s Pathology. Contract No.: THECB#9424. 7/01/2012 – 8/31/2014.  $80,000.

 

Hale AM. Curtailment experiments to reduce bat mortality at the Wolf Ridge wind facility in north-central Texas (2011-2013). NextEra Energy Resources (Funded – $48,519)

Hale AM. NextEra Energy Wind Research Initiative: Phase 2 (2013-2015) (Co-PI with M. Slattery, V. Bennett, and B. Johnson) NextEra Energy Resources $510,300

Williams D.  Improvement of biological control agents for the monoecious biotype of hydrilla in the United States, (2013-2014)USACE $24,000

 

$96,838 of Intramural Grants

 Akkaraju G.  2012-2013 TCU Invests in Research: Porous Silicon Based Magnetically-Guided Drug Delivery Vehicles $12,000 (Co-PI with Dr. Jeff Coffer, Department of Chemistry, Texas Christian University.)

Akkaraju G. 2013-2014 TCU SERC, (Wareing, N.) Anti-inflammatory effects of Curcumin on human embryonic kidney cells $1,430

Akkaraju G. 2013-2014 TCU SERC, (Chelvanambi, M.) Screening of plant extracts to identify drugs against Hepatitis C virus NS5A $1,500

Akkaraju G. 2013-2014 TCU SERC, (Vouzas, A.) Design and validation of a drug screening assay against Hepatitis C virus NS3/4A $1,451

Akkaraju G. 2013-2014 TCU SERC, (Simkins, A.) Mechanism of Hepatitis C virus NS5A-mediated inhibition of the virus-induced IFN-beta gene expression $1,395

Akkaraju G. 2013-2014 TCU SERC, (Szymanski, K) Creating a stable cell line expressing Hepatitis C virus NS3/4A $1,412

 

Chumchal MM. Nutrient impacts on contaminant flux from aquatic ecosystems: Mercury speciation analysis.  Andrews Institute of Mathematics, Science and Technology Education Research Grant, $3,000, 2012-2013. Type: Research, Funded.

Chumchal MM. Nutrient impacts on contaminant flux from aquatic ecosystems. TCU Research and Creative Activities Fund Grant, $4,000, 2012-2013. Type: Research, Funded.

Chumchal MM. Insect mediated transfer of aquatic mercury to terrestrial systems. M. Lewis and M. Chumchal. Science and Engineering Research Center – Undergraduate Research Grant Program Grant, $1,500, 2012-2013. Type: Research, Funded.

Chumchal MM. Determination of methyl mercury (MeHg) movement between aquatic and terrestrial ecosystems via stable isotope analysis. S. Speir and M. Chumchal. Science and Engineering Research Center – Undergraduate Research Grant Program Grant, $1,500, 2012-2013. Type: Research, Funded.

Chumley MJ. TCU RCAF #60655, Research award, TCU Office of Research and Creative Scholarship, $4,000.

Chumley MJ. TCU Invests In Scholarship Grant, Research Award, TCU Office of Research and Creative Scholarship, $4,000.

Chumley MJ. 2013-2014 TCU SERC, (Gardner, G) The effect of 7 days of LPS injections on the amount of pTau in the mouse brain      $1,000

Chumley MJ. 2013-2014 TCU SERC, (Gurney, T) The Effectiveness of the Antioxidant Pyclen-OH in the Disaggregation of A plaques, Reduction of Oxidative Stress, and Restoration of Cognitive Function in Alzheimer’s Disease $1,000

Chumley MJ. 2013-2014 TCU SERC, (Hayes, H) The Expression of NR4A Family mRNA in the Hippocampus following Peripheral Inflammation $1,000

Chumley MJ. 2013-2014 TCU SERC, (Mussatto, J) Analysis of amyloid beta clearance in exercised mice following inflammation $1,000

Chumley MJ. 2013-2014 TCU SERC, (Turner, S) Exercise-induced clearance of amyloid-β mediated by NG2 expressing oligodrendroglial precursor cells $1,000

Chumley MJ. 2013-2014 TCU SERC, (Riddle, C) The Effects of EphB1 and EphB3 Proteins on Amyloid-Beta Plaque Formation and the Progression of Alzheimer’s Disease $1,200

Chumley MJ. 2013-2014 TCU SERC, (Robertson, T) The Role of NR4A Family Proteins in the Memory Enhancement seen in Alzheimer’s Disease Mouse Models Treated with Rolipram  $1,100

Chumley MJ. 2013-2014 TCU SERC, (Parnell, T) Changes in Expression of Alzheimer’s Disease-Related Heat Shock Proteins Following Inflammation $1,200

Chumley MJ. 2013-2014 TCU SERC, (Salisbury, J) Steroidal Anti-Inflammatories and Their Role in the Progression of Alzheimer’s Disease $900

Chumley MJ. 2013-2014 TCU SERC, (Canellos, C) The Effects of Ibuprofen Administration After Lipopolysaccharide Injections in Prevention of Cognitive Dysfunction and Alleviation of Central Accumulation of Amyloid-Beta $700

Chumley MJ. 2013-2014 TCU SERC, (Boren, B) The Role and Implications of Eph Receptors EphB1 and EphB3 in Alzheimer’s Disease $1,500

Chumley MJ. 2012-2013 TCU RCAF, The Effects of Viral Inflammation on Neuronal Health and the Onset of Alzheimer Disease Pathology           $4,000

Crenshaw, M. Applied for and was awarded $3,600 through a TCU Instructional Development Grant for the “Development of Anatomy and Physiology Laboratory”. The funds were used to purchase human models used in Biology 20204 and 20214 laboratory exercises.

Crenshaw, M. Co-authored a request with Stephanie Wallace for $6,115 to further development of the Anatomy and Physiology labs. The funds were awarded by the College of Science and Engineering to purchase hardware and software to be used in physiology experiments in both Biology 20204 and 20214.

 

Drenner, RW.  Relationship between Hg concentrations in fish and terrestrial spiders. M. Rightley, R. Drenner and M. Chumchal. Science and Engineering Research Center – Undergraduate Research Grant Program Grant, $1,500, 2013-2014. Funded.

Drenner, RW. Terrestrial spiders as biosentinels of mercury contamination in aquatic ecosystems. TCU RCAF Grant, $2,600, 2013-2014. Funded.

Hale AM.  Raising awareness of the diversity and ecology of bats in Texas (2012/2013).  Andrews Institute of Mathematics, Science & Technology Education Research Grant (Funded – $2,564).

Hale, AM.  Incorporating K-12 outreach into a conservation genetics study and restoration effort for the threatened Texas horned lizard, Phrynosoma cornutum (2012/2013).  Co-PI with D. Williams.  Andrews Institute of Mathematics, Science & Technology Education Research Grant (Funded – $2,564).

Horner JD.  2012-2013 TCU RCAF, Identifying cryptic species using genetic markers. $3779.  Funded.

McGillivray SM.  Connection between autolytic activity and antibiotic sensitivity in Bacillus anthracis. TCU RCAF. Funded $4000.

McGillivray, SM. 2013-2014 TCU SERC, (Jessica Learned): Susceptibility of Bacillus Anthracis to Antimicrobial Peptides. Funded $1401.

 McGillivrary, SM. 2013-2014 TCU SERC, (Mariah Green): Inability of mutant Bacillus anthracis to sequester iron from hemoglobin $1347.

Williams D.  2013-2012 TCU RCAF, Status and movement patterns of Texas horned lizards living in urban areas $4,000

Williams, D. 2013-2014 TCU IS,  Status and movement patterns of Texas horned lizards living in urban areas        $8,000

Williams, D. 2013-2014 TCU SERC, (Tanner Campbell): Genetic characterization of a new population of the critically endangered Puerto Rican Crested Toad $1,500

Williams, D. 2013-2014 TCU SERC, (Sharon Fronk):  Diet determination of Texas horned lizards through fecal DNA analyses $1,080

33 Oral Presentations/Posters at Scientific Meetings and Invited Seminars and Awards

Akkaraju, G., Wu, W.*, Chelvanambi, M.**, Toal, C** and Gleaton, S. J.* (2013) The mechanism by which Hepatitis C virus non-structural protein NS5A attenuates virus-induced activation of the interferon beta promoter. Poster presented at the 32nd Annual Meeting of the American Society for Virology in Pennsylvania State University, State College, PA, July 20-24.

Miller, S.E., Kishton, R.J., Mastro, K., Kelly, C., Powell, M., Linares, A.**, Chelvanambi, M.**, Gore, V.K., Akkaraju, G.R., Varadarajan, S., 2013, N3-methyladenine formation by estradiol conjugates with a DNA minor groove methylating agent: effect of structure on DNA methylation and cell toxicity.  Poster presented at SERMACS2013, Atlanta GA, Nov. 12-16.

Granitzer, P., Rumpf, K., Tian, Y., Akkaraju, G., Coffer, J., Poelt, P. and Reissner, M., 2013, Size-dependent assessment of Fe3O4-nanoparticles loaded into porous silicon. ECS Transactions (Presented at 224th ECS Meeting, Oct.27 – Nov.1, San Francisco, CA, Electrochemical/Chemical Deposition and Etching).

Christian, J.*, B.W. Matherne*, P.M. Holt**, M.M. Chumchal, A.P. Roberts, D.J. Hoeinghaus, A.A. Agostinho, L.C. Gomes, 2013, Effects of body size, trophic position and ecosystem type on mercury in fishes of the Upper Paraná River basin, Brazil, Texas A&M University Ecological Integration Symposium, College Station, Texas.

 

Chumchal, M., R. Drenner, B. Blackwell*, B. Henderson*, T. Jones*, B. Tweedy*, 2013, Emergent bugs, small ponds, big problem: A synthesis of recent studies examining MeHg contamination of aquatic macroinvertebrates and insect-mediated flux of MeHg from small ponds to terrestrial ecosystems, 11th International Conference on Mercury as a Global Pollutant, Edinburgh, Scotland.

Chumchal, M., R. Drenner, B. Blackwell*, G. Cocke*, B. Henderson*, T. Jones*, W. Nowlin and B.Tweedy*, 2013, Bottom-Up Nutrient and Top-Down Fish Impacts on Methylmercury Flux from Aquatic Ecosystems: A Synthesis of Recent Studies, American Fisheries Society Annual Meeting, Little Rock, Arkansas.

Drenner, R.W., M.M. Chumchal , C.M. Jones*, Christopher M. B. Lehmann, David A.Gay, David I. Donato, 2013, Effects of mercury deposition and coniferous forests on the mercury contamination of fish in the south central United States, 11th International Conference on Mercury as a Global Pollutant, Edinburgh, Scotland.

Drenner, R.W., M.M. Chumchal , C.M. Jones*, Christopher M. B. Lehmann, David A.Gay, David I. Donato, 2013, Effects of mercury deposition and coniferous forests on the mercury contamination of fish in the south central United States, American Fisheries Society Annual Meeting, Little Rock, Arkansas.

Lavoie, R.A.*, T. Jardine, M.M. Chumchal, K. Kidd, L. Campbell, 2013, A Global Comparison of Mercury Biomagnification in Aquatic Ecosystems. Society for Environmental Toxicology and Chemistry Europe Meeting, Glasgow, Scotland.

Rainwater, T.R., M.M. Chumchal, L.J. Guillette, Jr., J. W. Gibbons, M.E. Dorcas, 2013, Circulating Mercury Concentrations in Diamondback Terrapins (Malaclemys terrapin) from Coastal South Carolina, 6th Symposium on the Ecology, Status & Conservation of Diamondback Terrapins, Seabrook Island, South Carolina.

Tweedy, B. N.*, R.W. Drenner, M.M. Chumchal, J.H. Kennedy, 2013, Effects of fish on emergent insect-mediated flux of methyl mercury across a gradient of contamination, Society for Freshwater Science Annual Meeting, Louisville, Kentucky.

Tweedy, B. N.*, R.W. Drenner, M.M. Chumchal, J.H. Kennedy, 2013, MeHg concentrations in a terrestrial spider, the long-jawed orb weaver (Tetragnatha sp.) are correlated with MeHg flux in emergent insects, 11th International Conference on Mercury as a Global Pollutant, Edinburgh, Scotland.

Weintraub, M.K.*, D. Kranjac*, M. J. Eimerbrink*, B. T. Vinson*, J. Patel**, W. Summers**, B. Womble**, G. W. Boehm, and M. J. Chumley, 2013, The Effects of Poly I:C on Hippocampal Amyloid-Beta and Cognition, Society for Neuroscience, San Diego, CA.

Weintraub, M. K.*, C. M. Bisson**, B. T. Vinson*, M. J. Eimerbrink*, D. Kranjac*, G. W. Boehmand M. J. Chumley, 2013, Imatinib methanesulfonate reduces hippocampal amyloid-beta and restores cognitive function following repeated endotoxin exposure. Psychoneuroimmunology Research Society, Stockholm, Sweden.

Weintraub, M. K.*, C. M. Bisson**, M. J. Chumley, 2013, Imatinib Reverses Amyloid Beta-Induced Cognitive Deficits.  Southwest Psychological Association, Fort Worth, TX.

Weintraub, M.K.*, M. J. Chumley, 2013, The Impact of Viral Inflammation on Alzheimer’s Disease-Like Pathology. Southwest Psychological Association, Fort Worth, TX.

Hale, A.M., T. Alison, and C. Hein, 2013, An overview of wind-wildlife research and information sources with implications for resource management, The Wildlife Society Annual Conference, Milwaukee, WI.Invited Symposium

Hale, A.M., A.M. McAlexander*, V.J. Bennett, and B.G. Cooper, 2013, A test of a novel attraction hypothesis – why are bats attracted to wind turbines? The Wildlife Society Annual Conference, Milwaukee, WI.

Bennett, V.J., and A.M. Hale, 2013, Site-specific wind turbine curtailment has its advantages,The Wildlife Society Annual Conference, Milwaukee, WI.

Hale, A.M., and V.J. Bennett, 2013, What can we learn from long-term post-construction fatality monitoring at a wind facility? The Wildlife Society Annual Conference, Milwaukee, WI.

Bennett, V.J., and A.M. Hale, 2013, Site-specific wind turbine curtailment has its advantages, 16th International Bat Research Conference & 43rd North American Symposium on Bat Research, San Jose, Costa Rica.

Hale, A.M., A.M. McAlexander*, V.J. Bennett, and B.G. Cooper, 2013, A test of a novel attraction hypothesis – why are bats attracted to wind turbines? 16th International Bat Research Conference & 43rd North American Symposium on Bat Research, San Jose, Costa Rica.

Sellin Jeffries M.K., A.E. Stultz, J. Rawlings, S. Belanger, and J.T. Oris, 2013, Webinar: Update on the development of alternative testing strategies and endpoints for determining whole effluent toxicity in fishes, Health and Environmental Science Institute Technical Committee Effluent Project Webinar.

Sellin Jeffries M.K., A.E. Stultz, J. Rawlings, S. Belanger, and J.T. Oris,  2013, The development of alternative strategies and additional endpoints for whole effluent toxicity testing in fishes, Society of Toxicology and Environmental Chemistry North America 34rd Annual Meeting, Nashville, TN.

Oris J.T., M.K. Sellin Jeffries, A.E. Stultz, J. Zhang, and A.J. Bailer, 2013, A Path Toward Effluent Toxicity Test Alternatives With Fish, Society of Toxicology and Environmental Chemistry North America 34rd Annual Meeting, Nashville, TN.

Thornton L.M.*, J.T. Oris, and M.K. Sellin Jeffries, 2013, Development of the sheepshead minnow, Cyprinodon variegatus, as a model organism for immunotoxicity, Society of Toxicology and Environmental Chemistry North America 34rd Annual Meeting, Nashville, TN.

Jones, G., 2013 “Causes, Criteria, and Testing for Diabetes Mellitus:  An Update.”  Presentation to the Texas State Society of Medical Technology Annual Meeting, Fort Worth, TX, Mar. 2013.

Barfield, K., Couch, E. and GC Kroh. 2013. Phylogeographic Study of Pinus ponderosa and P. jeffreyi. Texas Society for Microscopy Conference, Irving, Texas.

 

Claunch, K.C.** and S.M. McGillivray, 2013, Role of LrgAB in antibiotic resistance and autolytic activity in Bacillus anthracis and connection to the ClpXP protease, North Texas Research Symposium, Fort Worth, TX.

Franks, S.E.*, C. Ebrahimi, A. Hollands, C.Y. Okumura, R.V. Aroian, V. Nizet, and S.M. McGillivray, 2013, Use of Caenorhabditis elegans to identify a novel role for tellurium resistance genes in the pathogenesis of Bacillus anthracis, International Conference on Bacillus anthracis, B. cereus, and B. thuringiensis, Victoria, British Columbia, Canada.

Evans, C.R.*, E. Couch, and S.M. McGillivray, 2013,The effect of media conditions on cell wall thickness and cell division of Bacillus anthracis lacking ClpX, Texas Society of Microscopy, Irving, TX.

 

Sawey, M.R., Sawey, A.T.  2013. Using Wikispaces for collaborative content creation in a non-major’s Biology lab. Life Discovery-Doing Science: Exploring Biology for a Changing World. Ecological Society of America. St. Paul, MN.

 

Biffi, D.O. and D.A. Williams, 2013, Distribución espacial y patrones de uso de letrinas de nutrias marinas Lontra felina en Lima, Moquegua y Tacna. Segundo Encuentro de Investigadores Ambientales. Arequipa, Peru.

57 TCU Undergraduate Students Conducted Research with Biology Faculty

 

Akkaraju

  • Astrid Linares
  • Nancy Wareing
  • Coralee Toal
  • Manoj Chelvanambi
  • Athanasios Vouzas
  • Kyle Szymanski
  • Allison Simkins

Chumchal/Drenner

  • Meghan Lewis
  • Shannon Speir
  • Holly Whitt
  • Natalie Farha
  • Joan Fernandez
  • Cameron Keylor
  • Madison Rightley
  • Stephen O’Neal
  • Milan Podrecca
  • Graydon Wyatt
  • Shelby Creager
  • Kiefer Hazard
  • Trey Swinney
  • Ian Bryant
  • Conner Glass

Chumley

  • Stephanie Turner
  • Hailey Hayes
  • Laurel Gardner
  • Troy Gurney
  • Christine Riddle
  • Brock Boren
  • Thomas Parnell
  • Tanner Robertson
  • Ceci Canelos
  • Jenelle Salisbury
  • Courtney Bisson
  • Jigna Patel

Hale

  • Victoria Nettles
  • Kelsey Bailey
  • Sarah Beard

Horner

  • Ben Schatz
  • Brandon Zsigray

Jefferies

  • Michael Vaughan
  • Dane Stephens

McGillivray

  • Kevin Claunch
  • Mariah Green
  • Madison Rogan
  • Jessica Learned

 

Misamore

  • Tariq Al-Farrar
  • Chris Ganson
  • Ben Clifford
  • Elizabeth St. Laurent
  • Alex Erker
  • James Reichert
  • Omar Kahn
  • Caitlin Lange

 

Williams

  • Tanner Campbell
  • Shaun Jiang
  • Lizzy Do
  • Sharon Fronk

19 TCU Graduate Students Worked on MS Degrees with Biology Faculty

 

Akkaraju

  • Wenjing Lily Wu

Chumchal/Drenner

  • Gary Cocke
  • Taylor Jones
  • Kimberly Adams
  • Gretchen Gann
  • Cleve Powell
  • Frank Greenhill

Chumley

  • Marielle Weintraub
  • Scott Pearson
  • Ben Vinson

 

Hale

  • C. Danielle Cochran
  • Aaron McAlexander
  • Lauren Wyatt (M.A., outreach project)

 

Jefferies

  • Leah Thornton

McGillivray

  • Chris Evans
  • Elizabeth Franks

Williams

  • Daniella Biffi
  • Ashley Wall
  • Carolina Granthon

The Biology Department had a very productive year for 2012.    The following is our 2012 annual report.

Teaching:
Sixteen faculty members in Biology generated 8856 credit hours or over nine million dollars of tuition. In addition, biology faculty mentored 26 undergraduate and 13 MS graduate students in research. While rewarding and central to our Department’s mission, the mentorship of students in research is time consuming and a significant part of the teaching effort of the Department.

Scholarship:
The record of scholarship in the Department was very good. During 2012, the faculty published 10 peer-reviewed papers, had $523,163 of extramural funding, $53,471 of intramural funding, and presented 45 papers at scientific meetings or invited seminars.

Service:
Biology faculty advised 625 students.
Biologists played an important role on the PreHealth Committee, including conducting 38 mock interviews to prepare students for interviews at medical schools. Dr. Phil Hartman continued to serve as Chair of the PreHealth Committee.
Biology faculty reviewed 26 manuscripts and grants

Awards:

Below is a summary of the Department’s scholarship and student mentoring, compiled from faculty annual reports.

10 Published Papers

  1. Silicon Nanowire/Polycaprolactone Composites and Their Impact on Stromal Cell Function. Jiang, K.; Akkaraju, G.; Coffer, J., Journal of Materials Research (2012) DOI: http://dx.doi.org/10.1557/jmr.2012.265
  2. Fry, B., M.M. Chumchal. 2012. Mercury bioaccumulation in estuarine food webs. Ecological Applications, 22: 606–623.
  3. Henderson, B.L.*, M.M. Chumchal, R.W. Drenner, Y.Deng,** P.Diaz*, W.H. Nowlin. 2012 Effects of fish on mercury contamination of macroinvertebrate communities of grassland ponds. Environmental Toxicology and Chemistry 31: 870-876.
  4. Rubenstahl TG, AM Hale, KB Karsten. In Press. Scissor-tailed Flycatcher (Tyrannus forficatus) nesting success at a north Texas wind farm. Southwestern Naturalist.
  5. Williams DA, C Leach, AM Hale, KB Karsten, E Mujica, D Barber, LA Linam, N Rains. 2012. Development of tetranucleotide microsatellite loci and a non-invasive DNA sampling method for Texas horned lizards (Phrynosma cornutum). Conservation Genetics Resources 4:43-45. doi: 10.1007/s12686-011-9469-5.
  6. Onouchi, H., T. Ishii, M. Miyazawa, Y. Uchino, K. Yasuda, P.S. Hartman, K. Kawai, K.
  7. Tsubota and N. Ishii. Mitochondrial superoxide anion overproduction in Tet-mev-1 transgenic mice accelerates age-dependent corneal cell dysfunctions. Investig. Ophthalmol.& Viual Science 53, 5780-5787.
  8. Horner, J. D., J. C. Steele, C. Underwood, and D. Lingamfelter. 2012. Age-related changes in characteristics and prey capture of seasonal cohorts of Sarracenia alata pitchers. American Midland Naturalist 167: 13-27.
  9. McGillivray SM, Tran DN, Ramadoss NS, Alumasa JN, Okumura CY, Sakoulas G, Vaughn MM*, Zhang DX, Keiler KC, Nizet V. Pharmacological inhibition of the ClpXP protease increases bacterial susceptibility to host cathelicidin antimicrobial peptides and cell-envelope active antibiotics. Antimicrobial Agents and Chemotherapy 56 (4):1854-61
  10. Quinteros-Casaverde N, CF Flores-Negrón, and DA Williams. 2012. Low genetic diversity and fragmentation effects in a wind-pollinated tree, Polylepis multijuga Plige (Rosaceae) in the high Andes. Conservation Genetics 13:593–603.
  11. Williams DA, M Hanson, R Diaz and WA Overholt. 2012. Determination of common reed (Phragmites australis (Cav.) Trin. Ex Steudel) varieties in Florida. Journal of Aquatic Plant Management 50:69-74.

45 Oral Presentations/Posters at Scientific Meetings and Invited Seminars and Awards

  1. Chumchal, M.M., T.A. Jones*, R.W. Drenner, G.N. Timmins, and W.H. Nowlin. 2012. Bottom-up and top-down impacts on mercury flux from aquatic ecosystems. Society for Environmental Toxicology and Chemistry North America Meeting. Long Beach, California.
  2. Chumchal, M.M., T.A. Jones*, R.W. Drenner, G.N. Timmins, and W.H. Nowlin. 2012. Bottom-up and top-down impacts on contaminant flux from aquatic ecosystems. Society for Freshwater Science Annual Meeting. Louisville, Kentucky.
  3. Chumchal, M.M., T.A. Jones*, R.W. Drenner, G.N. Timmins, and W.H. Nowlin. 2012. Bottom-up and top-down impacts on contaminant flux from aquatic ecosystems. Society of Environmental Toxicology and Chemistry-South-Central Regional Chapter. Waco, Texas.
  4. Chumchal, M.M., T.A. Jones*, R.W. Drenner, G.N. Timmins, and W.H. Nowlin. 2012. Bottom-up and top-down impacts on contaminant flux from aquatic ecosystems. Texas Chapter of the American Fisheries Society Annual Meeting. Galveston, Texas.
  5. Drenner, R.W., M.M. Chumchal, S.P. Wente, C. Jones* and D. Donato. 2012. Landscape-level Patterns of Mercury Contamination of Fish in the South Central United States. Association of American Geographers Annual Meeting, New York City, New York.
  6. Drenner, R.W., M.M. Chumchal, C. Jones*, C. Lehmann, D. Gay and D. Donato. 2012. Landscape-level patterns of mercury contamination in the South Central United States. Eighth National Monitoring Conference, Portland, Oregon.
  7. Drenner, R.W., M.M. Chumchal, C. Jones*, C. Lehmann, D. Gay and D. Donato. 2012. Landscape-level patterns of mercury contamination in the South Central United States. Society of Environmental Toxicology and Chemistry-South-Central Regional Chapter. Waco, Texas.
  8. Lavoie,R.A.*, K. Kidd, T. Jardine, M.M. Chumchal, L. Campbell. 2012. Mercury biomagnification rate in aquatic food webs worldwide. Society for Environmental Toxicology and Chemistry North America Meeting. Long Beach, California
  9. Moore, B., N. Cook, H. Rushing, J. Cooper, E. Brinkman, A. Roberts, J. Smith, G. Verbeck, and M.M. Chumchal. 2012. Mercury bioaccumulation and associated liver pathologies in spotted gar. Gordon Research Conferences: Environmental Endocrine Disruptors. West Dover, Vermont.
  10. Park, A*, M.M. Chumchal, R.W. Drenner and T. Morgan. 2012. Effect of watershed land cover on mercury contamination in Big Cypress Watershed. Society of Environmental Toxicology and Chemistry-South-Central Regional Chapter. Waco, Texas.
  11. Roberts, A., M.M. Chumchal, P. Drevnick, K. Kidd, B. Moore, D.H. Adams, B. Barst*, J. Smith*, K. Batchelar*. 2012. Macrophage Centers: A Synthesis of Their Implications for Mercury Fate and Toxicity in Fish. Society for Environmental Toxicology and Chemistry North America Meeting. Long Beach, California.
  12. Tweedy, B.*, R.W. Drenner, M.M. Chumchal, and J. Kennedy. 2012. Effects of Fish on Insect Emergence and Transport of Methyl Mercury from Ponds Society of Environmental Toxicology and Chemistry-South-Central Regional Chapter. Waco, Texas.
  13. Marielle S Kahn, Courtney Bisson, Jessica Nouri, Benjamin Vinson, Dinko Kranjac, Micah Eimerbrink, Gary W Boehm, Michael J Chumley, Ph.D.
  14. EFFECTS OF IMATINIB METHANESULFONATE ON INFLAMMATION-INDUCED AMYLOID-BETA PRODUCTION AND COGNITION. October, 2012, New Orleans, LA., Annual Meeting of the Society for Neuroscience
  15. Marielle Kahn, Whitney Summers, Dinko Kranjac, Benjamin Vinson, Micah Eimerbrink, Gary Boehm, Michael Chumley. A POTENTIAL LINK BETWEEN VIRAL INFLAMMATION AND ALZHEIMER’S DISEASE. October, 2012, New Orleans, LA., Annual Meeting of the Society for Neuroscience. (first year listed)
  16. Courtney Bisson, Marielle Kahn, Jessica Nouri, Benjamin Vinson, Dinko Kranjac, Micah Eimerbrink, Gary W Boehm, Michael J Chumley, Ph.D. GLEEVEC ATTENUATES INFLAMMATION-INDUCED AMYLOID-BETA PRODUCTION AND RESTORES COGNITION. November, 2012, Fort Worth, TX., North Texas Life Science Research Symposium (first year listed)
  17. Whitney Summers, Marielle Kahn, Dinko Kranjac, Benjamin Vinson, Micah Eimerbrink, Gary Boehm, Michael Chumley. VIRAL INFLAMMATION AND THE ONSET OF ALZHEIMER’S DISEASE. November, 2012, Fort Worth, TX., North Texas Life Science Research Symposium (first year listed)
  18. Hale AM, JM Korstian, VJ Bennett, and DA Williams. 2012. Can genetics and stable isotopes be used to gain geographical insights into the seasonal movement patterns and population structure of eastern red bats (Lasiurus borealis)? National Wind Coordinating Collaborative Wind Wildlife Research Meeting IX. Denver, CO.
  19. Bennett VJ, and Hale AM. 2012. Can resource and activity hotspot mapping predict bat fatalities at wind turbines? National Wind Coordinating Collaborative Wind Wildlife Research Meeting IX. Denver, CO.
  20. Bennett VJ, C Sutter, AM Hale, A Costello, and K Heist. 2012. Can bat fatality be predicted from bat acoustic activity within the rotor-swept zone? National Wind Coordinating Collaborative Wind Wildlife Research Meeting IX. Denver, CO.
  21. Bennett VJ, C Sutter, AM Hale, A Costello, and K Heist. 2012. Can species-specific acoustic activity be relied upon to predict bat fatality at wind turbines? North American Society for Bat Research 42nd Annual Symposium. San Juan, Puerto Rico.
  22. Korstian J, A Hale, V Bennett, and D Williams. 2012. A genetic method to determine the sex of Lasiurus bat carcasses found at wind farms. North American Society for Bat Research 42nd Annual Symposium. San Juan, Puerto Rico.
  23. Bennett VJ, and AM Hale. 2012. The use of resource and activity hotspot mapping to predict bat-wind turbine interactions. The Wildlife Society Annual Meeting. Portland, OR.
  24. Bennett VJ, and AM Hale. 2012. The use of resource and activity hotspot mapping to predict bat-wind turbine interactions. American Society of Mammalogists Annual Meeting. Reno, NV.
  25. Korstian J, AM Hale, and DA Williams. 2012 High diversity and lack of genetic structure in eastern red bats (Lasiurus borealis). American Society of Mammalogists Annual Meeting. Reno, NV.
  26. Hale AM, KB Karsten, JA Meyer, ES Hatchett, TG Rubenstahl, TK Stevens, and VJ Bennett. 2012. Limited indirect effects of wind turbines on resident birds. AWEA WindPower 2012 Conference & Exhibition. Atlanta, GA.
  27. Bennett VJ, and Hale AM. 2012. Exploring ways to make wind turbines more bat friendly, both physically and operationally. AWEA WindPower 2012 Conference & Exhibition. Atlanta, GA.
  28. Hale AM, KB Karsten, and VJ Bennett. 2012. Recommendations for fatality monitoring studies at utility-scale wind farms. Association of American Geographers Annual Meeting. New York, NY.
  29. Bennett VJ, AM Hale, and KB Karsten. 2012. Toward an understanding of the effects of wind turbines on bats. Association of American Geographers Annual Meeting. New York, NY.
  30. Hatchett E, AM Hale, and KB Karsten. 2012. No effect of wind turbines on density and nest success of Dickcissels (Spiza americana) in north Texas. Association of American Geographers Annual Meeting. New York, NY.
  31. Korstian J, DA Williams, AM Hale, and VJ Bennett. 2012. Population genetics of migrating eastern red bats (Lasiurus borealis). Association of American Geographers Annual Meeting. New York, NY.
  32. Stevens TK, AM Hale, KB Karsten, and VJ Bennett. 2012. The effects of wind energy on over-wintering grassland birds. Association of American Geographers Annual Meeting. New York, NY.
  33. Karsten KB, and AM Hale. 2012. Using meteorological data to predict bat mortality at a wind facility in Texas. Society for Integrative and Comparative Biology Annual Meeting. Charleston, NC.
  34. Jones, Gail I., “Causes, Criteria, and Testing for Diabetes Mellitus: An Update.” Presentation to the Texas State Society of Medical Technology Annual Meeting, Fort Worth, TX, Mar. 2012.
  35. Poster presentation. Evans CR**, McGillivray SM. Role of ClpXP Protease on Bacillus anthracis Resistance to Cell Wall-Acting Antimicrobials. North Texas Research Symposium. Fort Worth TX. November 3 2012.
  36. Poster presentation. The role of tellurium resistance genes in the virulence of Bacillus anthracis. Franks, SE**, Ebrahimi C, Hollands A, Okumura CY, Aroian R, Nizet V and McGillivray SM. North Texas Research Symposium. Fort Worth TX. November 3 2012.
  37. Poster presentation. Rosati R*, McGillivray SM. The role of ClpX in Bacillus anthracis cell charge. North Texas Research Symposium. Fort Worth TX. November 3 2012.
  38. Poster presentation. Manceras J*, McGillivray SM. Discovery of novel iron acquisition genes in B. anthracis. North Texas Research Symposium. Fort Worth TX. November 3 2012.
  39. Oral presentation. The role of tellurium resistance genes in the virulence of Bacillus anthracis. Franks, SE**, Ebrahimi C, Hollands A, Okumura CY, Aroian R, Nizet V and McGillivray SM. Texas Branch of the American Society of Microbiology. Baylor TX. October 18-20, 2012.
  40. Poster presentation. Evans CR**, McGillivray SM. Role of ClpXP Protease on Bacillus anthracis Resistance to Cell Wall-Acting Antimicrobials. Texas Branch of the American Society of Microbiology. Baylor TX. October 18-20, 2012.
  41. Poster presentation. Manceras J*, McGillivray SM. Discovery of novel iron acquisition genes in B. anthracis. Texas Branch of the American Society of Microbiology. Baylor TX. October 18-20, 2012.
  42. Oral presentation. Evans CR**, Ernest Couch, McGillivray SM. Investigation of the cell wall structure of ΔClpX Bacillus anthracis. Texas Society of Microscopy, Fort Worth, TX. April 12-14 2012.
  43. Oral presentation. Franks, SE**, Ebrahimi C, Ernest Couch, Aroian R, Nizet V and McGillivray SM. Discovery of Novel Virulence Factors in Bacillus anthracis. Texas Society of Microscopy, Fort Worth TX. April 12-14 2012.
  44. Poster Presentation. Evans CR**, Flanigan SE*, McGillivray SM. Role of the ClpXP protease in the susceptibility of Bacillus anthracis to antimicrobial agents. 112th General Meeting of the American Society for Microbiology. San Francisco CA. June 16-19 2012.
  45. Invited Speaker, National Shellfish Meeting, Seattle WA. (2012). Early developmental events in the zebra and quagga mussels and possible targets for control. Michael J. Misamore.

$523,163 of External Grants

  • Chumchal MM. and Drenner RW
    • Watershed-Level Patterns of Mercury Contamination in the Caddo Lake Watershed and Other Areas of North Texas: Phase 1, Caddo Lake Institute, M. Chumchal and R. Drenner, Primary Investigators, $5,000, 2012. Type: Research, Funded.
    • Wind Turbine Impacts on Birds and Bats; TCU-University of Oxford-NextEra Energy Wind Research Initiative, M. Slattery, Primary Investigator. $8,856.12 sub-award for Effects of fish on mercury transport out of experimental ponds by invertebrates to M. Chumchal, 2012. Type: Research, Funded.
  • Chumley, M J.
    • Norman Hackerman Advanced Research Program.
    • Project Title: Systemic Inflammation as a Treatable Risk Factor in the Onset of Alzheimer’s Pathology. Contract No.: THECB#9424. 7/01/2012 – 8/31/2014. $80,000.
  • Hale AM.
    • Test of a novel hypothesis: why are bats attracted to wind turbines? (2011-2013) NextEra Energy Resources (Funded – $39,075)
    • Curtailment experiments to reduce bat mortality at the Wolf Ridge wind facility in north-central Texas (2011-2013). NextEra Energy Resources (Funded – $197,000)
    • Research Team Leader – Wind Turbine Impacts on Birds and Bats; TCU, University of Oxford, FPL Energy Wind Research Initiative (2008-2012), PI – Michael Slattery. (Funded – 2011: $149,613 for salaries, research expenses, and equipment).
  • Misamore MJ.
    • UV Treatment Technologies for Invasive Mussel Control”. Michael J. Misamore. United States Geological Survey. Awarded $31,078
    • Sterile male release technique (SMRT) with irradiation as a potential novel method for attenuating invasive quagga mussels – A laboratory experiment. Mike Misamore1, David Wong2, Shawn Gerstenberger2, Steen Madsen3. 1Department of Biology, Texas Christian University, 2Department of Environmental and Occupational Health, University of Nevada Las Vegas, 3Department of Physical Therapy, University of Nevada Las Vegas. Grant Submitted through the University of Nevada Las Vegas to the Utah Division of Wildlife Resources. Awarded $3,541 starting Jan.1, 2011.
  • Williams D.
    • 2012 The Rufford Small Grants Foundation. Developing a simple census method for endangered marine otters Lontra felina. DO Biffi and DA WIlliams. $9,000.

$53,471 of Intramural Grants

  • Akkaraju G.
    • TCU RCAF. Project title: Developing drugs with increased specificity for estrogen receptor expressing breast cancer cells. Amount: $4000
    • TCU invests in research: $12,000
  • Chumchal MM.
    • Nutrient impacts on contaminant flux from aquatic ecosystems: Mercury speciation analysis. Andrews Institute of Mathematics, Science and Technology Education Research Grant, $3,000, 2012-2013. Type: Research, Funded.
    • Nutrient impacts on contaminant flux from aquatic ecosystems. TCU Research and Creative Activities Fund Grant, $4,000, 2012-2013. Type: Research, Funded.
    • Insect mediated transfer of aquatic mercury to terrestrial systems. M. Lewis and M. Chumchal. Science and Engineering Research Center – Undergraduate Research Grant Program Grant, $1,500, 2012-2013. Type: Research, Funded.
    • Determination of methyl mercury (MeHg) movement between aquatic and terrestrial ecosystems via stable isotope analysis. S. Speir and M. Chumchal. Science and Engineering Research Center – Undergraduate Research Grant Program Grant, $1,500, 2012-2013. Type: Research, Funded.
  • Chumley MJ.
    • TCU RCAF #60655, Research award, TCU Office of Research and Creative Scholarship, $4,000.
    • TCU Invests In Scholarship Grant, Research Award, TCU Office of Research and Creative Scholarship, $4,000.
  • Hale AM.
    • Raising awareness of the diversity and ecology of bats in Texas (2012/2013). Andrews Institute of Mathematics, Science & Technology Education Research Grant (Funded – $2,564).
    • Incorporating K-12 outreach into a conservation genetics study and restoration effort for the threatened Texas horned lizard, Phrynosoma cornutum (2012/2013). Co-PI with D. Williams. Andrews Institute of Mathematics, Science & Technology Education Research Grant (Funded – $2,564).
  • Horner JD.
    • TCU RCAF. Identifying cryptic species using genetic markers. $3779. Funded.
  • McGillivray SM.
    • Role of the tellurium resistance genes in the pathogenesis of Bacillus anthracis. TCU RCAF. Amount requested and funded $4000.
  • Williams D.
    • 2012 RCAF. Genetic basis of herbicide resistance in the invasive aquatic weed, Hydrilla verticillata, $4,000.
    • 2012 Andrews Fellowship. Incorporating K-12 outreach into a conservation genetics study of the threatened Texas horned lizard, Phrynosoma cornutum, with A Hale $2,564.00.

Faculty Awards

  • Michael Chumley, Chosen as Honors Professor of the Year, Spring 2013

26 TCU Undergraduate Students Conducted Research with Biology Faculty

Chumchal

  • Meghan Lewis
  • Jack O’Brien
  • Shannon Speir
  • Holly Whitt

Chumley

  • Whitney Summers
  • Jigna Patel
  • Clay Fox
  • Janelle Salisbury
  • Courtney Bisson
  • Ceci Cannelos
  • Christine Riddle
  • Brock Boren
  • Tanner Roberston
  • Thomas Parnell

Hale

  • Victoria Nettles
  • Alison Schildt
  • Kelsey Bailey

Horner

  • Ben Schatz

McGillivray

  • Julio Manceras
  • Renee Rosati
  • Kevin Claunch

Misamore

  • John Avila
  • Nathan Cress
  • Zair Shag
  • Tariq Al-Farrar
  • Chris Ganson

13 TCU Graduate Students Worked on MS Degrees with Biology Faculty

  • Akkaraju
  • Wenjing Wu
  • Chumchal
  • Taylor Jones
  • Gary Cocke

Chumley

  • Marielle Kahn
  • Scott Pearson
  • Ben Vinson

Hale

  • Danielle Cochran
  • Aaron McAlexander
  • Lauren Wyatt

McGillivray

  • Elizabeth Franks
  • Chris Evans

Williams

  • Daniella Biffi
  • Ashley Wall